Q6J577 · Q6J577_BARBA
- ProteinUDP-N-acetylenolpyruvoylglucosamine reductase
- GenemurB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids325 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation.
Catalytic activity
- UDP-N-acetyl-alpha-D-muramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH + H+
Cofactor
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 186 | |||||
Sequence: R | ||||||
Active site | 235 | Proton donor | ||||
Sequence: S | ||||||
Active site | 305 | |||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | FAD binding | |
Molecular Function | UDP-N-acetylmuramate dehydrogenase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-N-acetylenolpyruvoylglucosamine reductase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Bartonellaceae > Bartonella
Accessions
- Primary accessionQ6J577
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 40-221 | FAD-binding PCMH-type | ||||
Sequence: RTGGLAELFYQPADEDDLSLFFKVLPEFVPVTIGGIGSNLLVRDGGIPGVVIRLSTKSFGQIKQVSSTRFLVGAATADKHLASAALEAEISGFHFYHGIPGGLGGALKMNAGANGVETAERVVEVYALDRKGERHILNLRDMNYAYRHCNIPEGLVFTAALLEGDVGNKDDIRAAMHEVALH |
Sequence similarities
Belongs to the MurB family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length325
- Mass (Da)35,961
- Last updated2004-07-05 v1
- Checksum8C7A3C233E03CA48