Q6G5J7 · DER_BARHE
- ProteinGTPase Der
- Geneder
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids475 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
GTPase that plays an essential role in the late steps of ribosome biogenesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 9-16 | GTP 1 (UniProtKB | ChEBI) | ||||
Sequence: GRPNVGKS | ||||||
Binding site | 56-60 | GTP 1 (UniProtKB | ChEBI) | ||||
Sequence: DTAGL | ||||||
Binding site | 119-122 | GTP 1 (UniProtKB | ChEBI) | ||||
Sequence: NKSE | ||||||
Binding site | 211-218 | GTP 2 (UniProtKB | ChEBI) | ||||
Sequence: GRPNTGKS | ||||||
Binding site | 258-262 | GTP 2 (UniProtKB | ChEBI) | ||||
Sequence: DTAGL | ||||||
Binding site | 323-326 | GTP 2 (UniProtKB | ChEBI) | ||||
Sequence: NKWD |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | GTP binding | |
Molecular Function | ribosome binding | |
Biological Process | ribosomal large subunit assembly |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameGTPase Der
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Bartonellaceae > Bartonella
Accessions
- Primary accessionQ6G5J7
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000011568 | 1-475 | GTPase Der | |||
Sequence: MSLTIAIVGRPNVGKSTLFNRLVGQKLALVDDKPGVTRDRRVHAATLQDLRFDVIDTAGLEETGDHTLEGRMRAHTKAAIDEADLILFVFDAKSGITPSDLNFASLVRKSGKPIVLVANKSESKAAIGGEYEAWSLGLGEPCSISAEHGLGLSDLRDAIMKASGGERIFASKNQEEHIALQSASLDDYIDNLEEKGDVYDKSKPLRIAVAGRPNTGKSTLINRMLGQDRLLTGPEAGLTRDSISVDWEWRGRHIKLFDTAGLRRKSKIQEKLEKLSVADTLRAIRFAEVVVIVFDATTPFEKQDLQIADLVIREGRVPLIAFNKWDLIENSQATLVDLHEKCIRLLPQVRGLRAVPLSGQYGQGIDKLMENVMMMHRVWNRRISTGKLNRWLETIVAHHPPPAVLGRRLKVKYVTQVKTRPPGFVFSCSRPKLMPQSYLRYLSNELRNTFDMPGIPIRISLRASDNPFATRSKKK |
Proteomic databases
Interaction
Subunit
Associates with the 50S ribosomal subunit.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-167 | EngA-type G 1 | ||||
Sequence: LTIAIVGRPNVGKSTLFNRLVGQKLALVDDKPGVTRDRRVHAATLQDLRFDVIDTAGLEETGDHTLEGRMRAHTKAAIDEADLILFVFDAKSGITPSDLNFASLVRKSGKPIVLVANKSESKAAIGGEYEAWSLGLGEPCSISAEHGLGLSDLRDAIMKASGGER | ||||||
Domain | 205-380 | EngA-type G 2 | ||||
Sequence: LRIAVAGRPNTGKSTLINRMLGQDRLLTGPEAGLTRDSISVDWEWRGRHIKLFDTAGLRRKSKIQEKLEKLSVADTLRAIRFAEVVVIVFDATTPFEKQDLQIADLVIREGRVPLIAFNKWDLIENSQATLVDLHEKCIRLLPQVRGLRAVPLSGQYGQGIDKLMENVMMMHRVWN | ||||||
Domain | 381-465 | KH-like | ||||
Sequence: RRISTGKLNRWLETIVAHHPPPAVLGRRLKVKYVTQVKTRPPGFVFSCSRPKLMPQSYLRYLSNELRNTFDMPGIPIRISLRASD |
Sequence similarities
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length475
- Mass (Da)52,968
- Last updated2004-07-19 v1
- ChecksumD68A7959BD3B613D
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BX897699 EMBL· GenBank· DDBJ | CAF27217.1 EMBL· GenBank· DDBJ | Genomic DNA |