Q632P8 · LUXS_BACCZ

Function

function

Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

Catalytic activity

Cofactor

Fe cation (UniProtKB | Rhea| CHEBI:24875 )

Note: Binds 1 Fe cation per subunit.

Features

Showing features for binding site.

115720406080100120140
TypeIDPosition(s)Description
Binding site54Fe cation (UniProtKB | ChEBI)
Binding site58Fe cation (UniProtKB | ChEBI)
Binding site126Fe cation (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functioniron ion binding
Molecular FunctionS-ribosylhomocysteine lyase activity
Biological Processquorum sensing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    S-ribosylhomocysteine lyase
  • EC number
  • Alternative names
    • AI-2 synthesis protein
    • Autoinducer-2 production protein LuxS

Gene names

    • Name
      luxS
    • Ordered locus names
      BCE33L4544

Organism names

Accessions

  • Primary accession
    Q632P8

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001722071-157S-ribosylhomocysteine lyase

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Sequence similarities

Belongs to the LuxS family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    157
  • Mass (Da)
    17,856
  • Last updated
    2004-10-25 v1
  • Checksum
    5D2BB8F36D754793
MPSVESFELDHTIVKAPYVRHCGVHNVGSDGIVNKFDIRFCQPNKQAMKPDVIHTLEHLLAFNLRKYIDRYPHFDIIDISPMGCQTGYYLVVSGTPTVREIIDLLELTLKDAVQITEIPAANETQCGQAKLHDLEGAKRLMNFWLSQDKDELEKVFG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000001
EMBL· GenBank· DDBJ
AAU15729.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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