Q631P3 · FLUC2_BACCZ
- ProteinFluoride-specific ion channel FluC 2
- GenefluC2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids118 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC 2
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus > Bacillus cereus group
Accessions
- Primary accessionQ631P3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 1-21 | Helical | ||||
Sequence: MIEALLVATGGFFGAITRFAI | ||||||
Transmembrane | 33-53 | Helical | ||||
Sequence: FPIATFLINITGAFLLGYIIG | ||||||
Transmembrane | 55-75 | Helical | ||||
Sequence: GVTTGWQLLLGTGFMGAFTTF | ||||||
Transmembrane | 93-113 | Helical | ||||
Sequence: TFLLYLSATYIVGILFAFLGM |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000110046 | 1-118 | Fluoride-specific ion channel FluC 2 | |||
Sequence: MIEALLVATGGFFGAITRFAISNWFKKRNKTSFPIATFLINITGAFLLGYIIGSGVTTGWQLLLGTGFMGAFTTFSTFKLESVQLLNRKNFSTFLLYLSATYIVGILFAFLGMQLGGI |
Structure
Sequence
- Sequence statusComplete
- Length118
- Mass (Da)12,885
- Last updated2004-10-25 v1
- ChecksumC80DD0ADA106470B
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000001 EMBL· GenBank· DDBJ | AAU15472.1 EMBL· GenBank· DDBJ | Genomic DNA |