Q56582 · NQRC_VIBAL

  • Protein
    Na(+)-translocating NADH-quinone reductase subunit C
  • Gene
    nqrC
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    5/5

Function

function

NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na+ ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

Catalytic activity

Cofactor

FMN (UniProtKB | Rhea| CHEBI:58210 )

Activity regulation

This reaction is tightly coupled to the Na+ pumping activity and specifically requires Na+ for activity. Inhibited by korormicin and 2-N-heptyl-4-hydroxyquinoline N-oxide (HQNO).

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular FunctionFMN binding
Molecular Functionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Protein family/group databases

    • 3.D.5.1.1the na+-translocating nadh:quinone dehydrogenase (na-ndh or nqr) family

Names & Taxonomy

Protein names

  • Recommended name
    Na(+)-translocating NADH-quinone reductase subunit C
  • EC number
  • Short names
    Na(+)-NQR subunit C
    ; Na(+)-translocating NQR subunit C
  • Alternative names
    • NQR complex subunit C
    • NQR-1 subunit C

Gene names

    • Name
      nqrC
    • Synonyms
      nqr3

Organism names

  • Taxonomic identifier
  • Strain
    • NCIMB 11038 / LMG 3418
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Vibrionales > Vibrionaceae > Vibrio

Accessions

  • Primary accession
    Q56582
  • Secondary accessions
    • Q56566
    • Q56588

Subcellular Location

Cell inner membrane
; Single-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-32Helical

Keywords

PTM/Processing

Features

Showing features for initiator methionine, chain, modified residue.

TypeIDPosition(s)Description
Initiator methionine1Removed
ChainPRO_00002142212-256Na+-translocating NADH-quinone reductase subunit C
Modified residue224FMN phosphoryl threonine

Keywords

Interaction

Subunit

Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the NqrC family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    256
  • Mass (Da)
    27,703
  • Last updated
    2007-01-23 v3
  • Checksum
    150DCD862BCB7CE7
MASNNDSIKKTLGVVIGLSLVCSIIVSTAAVGLRDKQKANAVLDKQSKIVEVAGIDANGKKVPELFAEYIEPRLVDLETGNFTEGNASTYDQREASKDAERSIALTPEEDVADIRRRANTAVVYLVKDQDEVQKVILPMHGKGLWSMMYAFVAVETDGNTVSAITYYEQGETPGLGGEVENPSWRDQFIGKKLYNEDHQPAIKVVKGGAPQGSEHGVDGLSGATLTSNGVQHTFDFWLGDKGFGPFLAKVRDGELN

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict184in Ref. 1; CAA85478

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z37111
EMBL· GenBank· DDBJ
CAA85478.1
EMBL· GenBank· DDBJ
Genomic DNA
AB008030
EMBL· GenBank· DDBJ
BAA22912.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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