Q4D3E8 · RIBJ_TRYCC
- ProteinRiboflavin transporter RibJ
- GeneRibJ
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids472 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Transporter involved in riboflavin (vitamin B2) uptake. Also transports FMN and FAD.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | riboflavin transmembrane transporter activity | |
Biological Process | riboflavin transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameRiboflavin transporter RibJ
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Trypanosoma > Schizotrypanum
Accessions
- Primary accessionQ4D3E8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-11 | Cytoplasmic | ||||
Sequence: MLPCFTRKPVD | ||||||
Transmembrane | 12-32 | Helical | ||||
Sequence: HPLGFLVALSGLLMQLMSYGI | ||||||
Topological domain | 33-58 | Extracellular | ||||
Sequence: DNSYSIFSDDMHKDPSLGYPSVTTIS | ||||||
Transmembrane | 59-79 | Helical | ||||
Sequence: LGNSVSLGLSPAFGVLCGFLV | ||||||
Topological domain | 80-85 | Cytoplasmic | ||||
Sequence: DRVPPR | ||||||
Transmembrane | 86-106 | Helical | ||||
Sequence: LMMAVSTLMLFAGLWLSSTFA | ||||||
Topological domain | 107-108 | Extracellular | ||||
Sequence: HN | ||||||
Transmembrane | 109-129 | Helical | ||||
Sequence: VTAVTFSYCLLASISSACMLS | ||||||
Topological domain | 130-144 | Cytoplasmic | ||||
Sequence: PGAAATSSWFNRYQG | ||||||
Transmembrane | 145-165 | Helical | ||||
Sequence: LAMGINFSGGGVGSAIIPSLA | ||||||
Topological domain | 166-179 | Extracellular | ||||
Sequence: GKWVVAYGWRKTFR | ||||||
Transmembrane | 180-196 | Helical | ||||
Sequence: LMSAFCAIGVVATLLSA | ||||||
Topological domain | 197-271 | Cytoplasmic | ||||
Sequence: RRAPPKKEEAGPSEYDEGQERQEQGEEEQAHTDEENRNNNNSNGETTPARRGLHTHKLNPWELFLTMFSRAFLGN | ||||||
Transmembrane | 272-292 | Helical | ||||
Sequence: FFCWLIFSWAFYSLIYVAVPY | ||||||
Topological domain | 293-315 | Extracellular | ||||
Sequence: VSSMGKAGTVYADISPIPTDIAS | ||||||
Transmembrane | 316-336 | Helical | ||||
Sequence: TLFTFYGVFQIVGSILVGWLA | ||||||
Topological domain | 337-341 | Cytoplasmic | ||||
Sequence: TGTTN | ||||||
Transmembrane | 342-362 | Helical | ||||
Sequence: EFAYVLCATIGGIFCAFLGFC | ||||||
Topological domain | 363-365 | Extracellular | ||||
Sequence: RSY | ||||||
Transmembrane | 366-386 | Helical | ||||
Sequence: VAFALLLCVIGFCMAGMFAVM | ||||||
Topological domain | 387-399 | Cytoplasmic | ||||
Sequence: PALIAERLYGPNL | ||||||
Transmembrane | 400-420 | Helical | ||||
Sequence: GFYMGAVFLAGVVGGFSAPPI | ||||||
Topological domain | 421-434 | Extracellular | ||||
Sequence: QAELQQRHYGNYTY | ||||||
Transmembrane | 435-455 | Helical | ||||
Sequence: VCVFMSACMTLAAAVCYITMW | ||||||
Topological domain | 456-472 | Cytoplasmic | ||||
Sequence: RDKRVRIVSAAAEAKLA |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000442705 | 1-472 | Riboflavin transporter RibJ | |||
Sequence: MLPCFTRKPVDHPLGFLVALSGLLMQLMSYGIDNSYSIFSDDMHKDPSLGYPSVTTISLGNSVSLGLSPAFGVLCGFLVDRVPPRLMMAVSTLMLFAGLWLSSTFAHNVTAVTFSYCLLASISSACMLSPGAAATSSWFNRYQGLAMGINFSGGGVGSAIIPSLAGKWVVAYGWRKTFRLMSAFCAIGVVATLLSARRAPPKKEEAGPSEYDEGQERQEQGEEEQAHTDEENRNNNNSNGETTPARRGLHTHKLNPWELFLTMFSRAFLGNFFCWLIFSWAFYSLIYVAVPYVSSMGKAGTVYADISPIPTDIASTLFTFYGVFQIVGSILVGWLATGTTNEFAYVLCATIGGIFCAFLGFCRSYVAFALLLCVIGFCMAGMFAVMPALIAERLYGPNLGFYMGAVFLAGVVGGFSAPPIQAELQQRHYGNYTYVCVFMSACMTLAAAVCYITMWRDKRVRIVSAAAEAKLA | ||||||
Glycosylation | 108 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 431 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
PTM databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 200-231 | Basic and acidic residues | ||||
Sequence: PPKKEEAGPSEYDEGQERQEQGEEEQAHTDEE | ||||||
Region | 200-248 | Disordered | ||||
Sequence: PPKKEEAGPSEYDEGQERQEQGEEEQAHTDEENRNNNNSNGETTPARRG |
Sequence similarities
Belongs to the major facilitator superfamily. RibJ family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length472
- Mass (Da)51,218
- Last updated2005-09-13 v1
- ChecksumEF42ED0D12DD4774
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 200-231 | Basic and acidic residues | ||||
Sequence: PPKKEEAGPSEYDEGQERQEQGEEEQAHTDEE |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAHK01001096 EMBL· GenBank· DDBJ | EAN87055.1 EMBL· GenBank· DDBJ | Genomic DNA |