Q47LJ6 · RL2_THEFY

Function

function

One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosolic large ribosomal subunit
Molecular FunctionrRNA binding
Molecular Functionstructural constituent of ribosome
Molecular Functiontransferase activity
Biological Processcytoplasmic translation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Large ribosomal subunit protein uL2
  • Alternative names
    • 50S ribosomal protein L2

Gene names

    • Name
      rplB
    • Ordered locus names
      Tfu_2643

Organism names

Accessions

  • Primary accession
    Q47LJ6

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002372581-277Large ribosomal subunit protein uL2

Interaction

Subunit

Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region1-55Disordered
Compositional bias41-55Basic residues
Region217-277Disordered
Compositional bias263-277Basic residues

Sequence similarities

Belongs to the universal ribosomal protein uL2 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    277
  • Mass (Da)
    30,146
  • Last updated
    2005-09-13 v1
  • Checksum
    688A84AD255002B2
MGIRKYKPTSPGRRGGSVSTFAEITRSKPEKSLVRPLHSKGGRNGHGRITARHQGGGHKRAYRLIDFRRHDKDGIPAKVAHIEYDPNRTARIALLHYVDGEKRYILAPVGLKQGDRVENGPAADIKPGNCLPLRNIPTGTFVHAVELKPGGGAKLGRAAGAAIQLLAKEGAYATLRMPSGEMRQVEVACRATVGQVGNVEHANISWGKAGRMRWKGKRPSVRGVAMNPIDHPHGGGEGRTSGGRHPVSPWGKAEGRTRKKGKPSDRLIVRRRSKKKR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias41-55Basic residues
Compositional bias263-277Basic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000088
EMBL· GenBank· DDBJ
AAZ56676.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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