Q3YR04 · ARGC_EHRCJ
- ProteinN-acetyl-gamma-glutamyl-phosphate reductase
- GeneargC
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids346 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
Catalytic activity
- N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = H+ + N-acetyl-L-glutamyl 5-phosphate + NADPH
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; N2-acetyl-L-ornithine from L-glutamate: step 3/4.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 151 | |||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | N-acetyl-gamma-glutamyl-phosphate reductase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP+ binding | |
Biological Process | arginine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameN-acetyl-gamma-glutamyl-phosphate reductase
- EC number
- Short namesAGPR
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rickettsiales > Anaplasmataceae > Ehrlichia
Accessions
- Primary accessionQ3YR04
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000010993 | 1-346 | N-acetyl-gamma-glutamyl-phosphate reductase | |||
Sequence: MSYQVSVAVVGATGYVGVELVRLLLAHPMVKIRYLCATQSTGKLLSSSYFHISQNYISISVSSFDDIDLDKLDVVFLCLPHGASSEIVKKIHNVVKVIDLSADFRIKDPDIYKQWYGVHYCPDLIKDFVYGLTEIYYEDIQKSSFIACPGCYPTSVLIPLFPLLRLRLVKSNNIIVDAKSGVSGAGRSVKQDNLFCEVYDAIKSYKVSNHRHIPEIEQELCFAACREDINLQFVPNLIPVKRGMMSNIYLELEVGVSLTDVREALLLFYRDSFFVVVDEEKAITTRSVVGTNYCYLGIFPGRLPNTIVIISVIDNLLKGAAGQAVQNFNVMMSYEEKLALSNIPYF |
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence similarities
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length346
- Mass (Da)38,849
- Last updated2005-09-27 v1
- Checksum9B15964BFBC778D6
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000107 EMBL· GenBank· DDBJ | AAZ68851.1 EMBL· GenBank· DDBJ | Genomic DNA |