Q3B110 · YIDC_CHLL3
- ProteinMembrane protein insertase YidC
- GeneyidC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids585 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | membrane insertase activity | |
Biological Process | protein insertion into membrane | |
Biological Process | protein transport |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameMembrane protein insertase YidC
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Chlorobiota > Chlorobiia > Chlorobiales > Chlorobiaceae > Chlorobium/Pelodictyon group > Pelodictyon
Accessions
- Primary accessionQ3B110
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 5-25 | Helical | ||||
Sequence: SVTGLALIALIMIVWLQFMSP | ||||||
Transmembrane | 338-358 | Helical | ||||
Sequence: FGWDWLTRPFAEFVILPAFTW | ||||||
Transmembrane | 362-382 | Helical | ||||
Sequence: FVSNYGLIIIIFAFLIKLVTY | ||||||
Transmembrane | 432-452 | Helical | ||||
Sequence: LGGCLPVVLQMPLLFAMFYVF | ||||||
Transmembrane | 482-502 | Helical | ||||
Sequence: IPMYGSHIALLPILMAVTVFL | ||||||
Transmembrane | 518-538 | Helical | ||||
Sequence: IMLYMFPAMMLLFFNNMPSGL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000070132 | 1-585 | Membrane protein insertase YidC | |||
Sequence: MDRNSVTGLALIALIMIVWLQFMSPEKKPLQQVTDAGKARTEQVAAEINSDMQPAAVPATEDSFGMFAPAASGTERLTVIDNDLFHAVVSSKGATLKSLVLKKHLDGNLKPFDLVSDAKNGALSMLFLTREGRRIDTRDLYFAGSSLDTLHTIKGKETYALSYRLALSPRQSIEVSYTFTGDSYRIGYDVKLTGLSGSLAGNEYQVQWDGGLPYTEKNRDDEARSAQASAYLGGSLVKLDAEKDGRSYREEQSGDARWVAVRNKYFIAALIPEDRTAGFYLDGQKERGNAYENYLASLKMEVPASEEVVDSRFSLYLGPLDYNTVKAQHADIEKIMDFGWDWLTRPFAEFVILPAFTWMNRFVSNYGLIIIIFAFLIKLVTYPLSTASTKSMKKMAALQPMLKELQDKYKDNPAKLQSELGRIYKEAGVNPLGGCLPVVLQMPLLFAMFYVFRSSIQLRQHGFLWVKDLSVPDSILDFGFTIPMYGSHIALLPILMAVTVFLQQKITPTAQSNDQMKIMLYMFPAMMLLFFNNMPSGLALYYLMFNVFSVAQQFYINSTSSAADLPQVSISAPSRPKKKKSGSGK |
Interaction
Subunit
Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length585
- Mass (Da)65,272
- Last updated2005-11-22 v1
- Checksum2557812683F22185
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000096 EMBL· GenBank· DDBJ | ABB24971.1 EMBL· GenBank· DDBJ | Genomic DNA |