Q3A9Q8 · RPOC_CARHZ

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site60Zn2+ 1 (UniProtKB | ChEBI)
Binding site62Zn2+ 1 (UniProtKB | ChEBI)
Binding site75Zn2+ 1 (UniProtKB | ChEBI)
Binding site78Zn2+ 1 (UniProtKB | ChEBI)
Binding site449Mg2+ (UniProtKB | ChEBI)
Binding site451Mg2+ (UniProtKB | ChEBI)
Binding site453Mg2+ (UniProtKB | ChEBI)
Binding site779Zn2+ 2 (UniProtKB | ChEBI)
Binding site853Zn2+ 2 (UniProtKB | ChEBI)
Binding site860Zn2+ 2 (UniProtKB | ChEBI)
Binding site863Zn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Molecular Functionmagnesium ion binding
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit beta'
  • EC number
  • Short names
    RNAP subunit beta'
  • Alternative names
    • RNA polymerase subunit beta'
    • Transcriptase subunit beta'

Gene names

    • Name
      rpoC
    • Ordered locus names
      CHY_2317

Organism names

Accessions

  • Primary accession
    Q3A9Q8

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002255221-1152DNA-directed RNA polymerase subunit beta'

Interaction

Subunit

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,152
  • Mass (Da)
    129,253
  • Last updated
    2005-11-22 v1
  • Checksum
    4544D52CF6FE3AA8
MLVLNNFERIKIGLASPDQIRAWSHGEVKKPETINYRTLKPERDGLFCERIFGPTKDWECHCGKYKRVRYKGVVCDRCGVEVTRSKVRRERLGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRSLEKVLYFVSYIVIDPGETPLLKKQLLTETEYREAREKYGNAFKAGMGAEAIKELLAEIDLDELSAELKAEIKESTGQRRIRALRRLEVVESFRKSGNRPEWMILDVIPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKEMALELFKPFVMKKLVADGIAHNIKSAKRMVERVKPEVWDVLEEVIKEHPVLLNRAPTLHRLGIQAFEPVLVEGRAIQIHPLVCTAYNADFDGDQMAVHVPLSAEAQAEARLLMLSSHNILNPKDGKPVVVPTQDMVIGSYYLTVEKPGAKGEGKKFAHPEEVIMAYEEGVIELHTKIKVRYPIRGEIVELETTPGRIIFNEVIPEELRFINHLVDKKALGKIVTESYRKLGYEKTGYLLDGLKKLGFHYATKAGLTIGIVDITVPKEKQEILEEADRMVADIEVKYRRGLITEDERYQRVVDIWNAATEKVTKKLVETLEASQFNHVYMMAKSGARGNIQQIRQLAGMRGLMADPSGRIIDLPIKANFREGLTVLEYFISTHGARKGLADTALRTADSGYLTRRLVDVCQDVIVREEDCGTEDGIYVTDVKDGTDVIEKLEDRILGRVAAEDVVHPETGELLVAKNQEITEEIAEKIVSANIKKVKIRSVLTCRTRHGVCTRCYGRNLATNSIVDIGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGEDITQGLPRVEELFEARRPKGQAIITEIDGVVEVRDNKGRREIEVINQETGERKVYPITYQARIKVQTGDKVYAGDELTEGPINPHDLIKVKGIEGAQLYLLQEVQKVYRMQGVEINDKHIEVVIRQMLRKVKIEDSGDTDLLPGSLVDIFEFEDENAKVIAKGGKPATAKRVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKVDPLLGLKENVIIGKLIPAGTGMARYRNIMVQAKNEE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000141
EMBL· GenBank· DDBJ
ABB15562.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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