Q32N32 · GOLM2_XENLA

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane

Names & Taxonomy

Protein names

  • Recommended name
    Protein GOLM2
  • Alternative names
    • Cancer susceptibility candidate gene 4 protein homolog (CASC4)
    • Golgi membrane protein 2

Gene names

    • Name
      golm2
    • Synonyms
      casc4

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus

Accessions

  • Primary accession
    Q32N32
  • Secondary accessions
    • Q7T0X8

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass type II membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-12Cytoplasmic
Transmembrane13-33Helical; Signal-anchor for type II membrane protein
Topological domain34-385Lumenal

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002918471-385Protein GOLM2

Expression

Gene expression databases

    • 379533Expressed in internal ear and 19 other cell types or tissues

Structure

Family & Domains

Features

Showing features for coiled coil, compositional bias, region.

TypeIDPosition(s)Description
Coiled coil44-193
Compositional bias169-220Basic and acidic residues
Region169-385Disordered
Compositional bias236-256Basic and acidic residues
Compositional bias257-283Polar residues
Compositional bias288-303Basic and acidic residues
Compositional bias323-337Polar residues
Compositional bias370-385Basic and acidic residues

Sequence similarities

Belongs to the GOLM family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

Q32N32-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    385
  • Mass (Da)
    43,974
  • Last updated
    2005-12-06 v1
  • Checksum
    20DFD1255964ED7D
MVGFGAPRRTGRLPPFVLVALLAVIGLLAFNYWSVSARQAALHDELLGLQAQVQRTEVARSRLEKRNSELMMQSDSHRRQIEQKQGEYQGLGERLQARDIQAQRCELDKSKLQNNVSLQMADISHLKEQLAELRHEFLRQEDQLHEYKNNNTFLQKSLQEESQQCAQQLAERKREYEENLTKQKEELDKQPQKDEEEGGTVDNKMHILPSEVKEKIEDPSSNRLPFAQDGIKLESDAGMPEIEDNEPAKEDSLQNDVKGQDTGALPSQSKSLLEKQPSLQPLSFTEHEVKKPLPDKKETVQIPEVEENALQLEPHPLKQMPRDSKTMSFNLKQSRFFDENESPVDPQHGSKVADYNGDDGNVEDDDHDGQADAGEYHKDHLNETL

Q32N32-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

Features

Showing features for sequence conflict, compositional bias, alternative sequence.

TypeIDPosition(s)Description
Sequence conflict114in Ref. 1; AAH55994
Compositional bias169-220Basic and acidic residues
Sequence conflict181in Ref. 1; AAH55994
Compositional bias236-256Basic and acidic residues
Compositional bias257-283Polar residues
Compositional bias288-303Basic and acidic residues
Compositional bias323-337Polar residues
Sequence conflict334in Ref. 1; AAH55994
Alternative sequenceVSP_026266335-363in isoform 2
Compositional bias370-385Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC055994
EMBL· GenBank· DDBJ
AAH55994.1
EMBL· GenBank· DDBJ
mRNA
BC108864
EMBL· GenBank· DDBJ
AAI08865.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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