Q31U23 · TRMA_SHIBS

Function

function

Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

Catalytic activity

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site190S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site218S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site223S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site239S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site299S-adenosyl-L-methionine (UniProtKB | ChEBI)
Active site324Nucleophile
Active site358Proton acceptor

GO annotations

AspectTerm
Molecular FunctiontRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent
Biological ProcesstRNA methylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA/tmRNA (uracil-C(5))-methyltransferase
  • EC number
  • Alternative names
    • tRNA (uracil(54)-C(5))-methyltransferase
    • tRNA(m5U54)-methyltransferase
      (RUMT
      )
    • tmRNA (uracil(341)-C(5))-methyltransferase

Gene names

    • Name
      trmA
    • Ordered locus names
      SBO_3984

Organism names

Accessions

  • Primary accession
    Q31U23

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002814641-366tRNA/tmRNA (uracil-C5)-methyltransferase

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    366
  • Mass (Da)
    41,953
  • Last updated
    2005-12-06 v1
  • Checksum
    40CCE34FE8695503
MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTKIALDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQFETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHKVERLALFDQFPYTHHMECGVLLTAK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000036
EMBL· GenBank· DDBJ
ABB68435.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp