Q2RK25 · DEF_MOOTA

Function

function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

Catalytic activity

Cofactor

Fe2+ (UniProtKB | Rhea| CHEBI:29033 )

Note: Binds 1 Fe2+ ion.

Features

Showing features for binding site, active site.

115520406080100120140
TypeIDPosition(s)Description
Binding site88Fe cation (UniProtKB | ChEBI)
Binding site130Fe cation (UniProtKB | ChEBI)
Active site131
Binding site134Fe cation (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular Functionpeptide deformylase activity
Biological Processpeptidyl-methionine modification
Biological Processtranslation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peptide deformylase
  • EC number
  • Short names
    PDF
  • Alternative names
    • Polypeptide deformylase

Gene names

    • Name
      def
    • Ordered locus names
      Moth_0897

Organism names

Accessions

  • Primary accession
    Q2RK25

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003010561-155Peptide deformylase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the polypeptide deformylase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    155
  • Mass (Da)
    16,851
  • Last updated
    2006-01-24 v1
  • Checksum
    9F0415CE4692EF7F
MAIHKILTLGDPLLREKSQPVRKITSNVWKLLDNLADTMYDAPGVGLAAPQIGVLKRVIVVDVGEGLTELINPEVIAASGEEVGAEGCLSIPGAQGEVPRAAVVTVRGLDRHGRVREIRAEGLYARALQHEIDHLDGILFIDKVVRWLENQPGER

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000232
EMBL· GenBank· DDBJ
ABC19214.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp