Q2KTC2 · MX_DICLA
- ProteinInterferon-induced GTP-binding protein Mx
- Genemx
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids652 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Features
Showing features for binding site.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Recommended nameInterferon-induced GTP-binding protein Mx
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Moronidae > Dicentrarchus
Accessions
- Primary accessionQ2KTC2
- Secondary accessions
Proteomes
Subcellular Location
Phenotypes & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | 239 | |||||
Sequence: M → V | ||||||
Natural variant | 457 | |||||
Sequence: K → R |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 2 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000292871 | 1-652 | Interferon-induced GTP-binding protein Mx | |||
Sequence: MNALNQQYEEKVRPCIDLIDSLRSLGVEKDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLELKMKRKNEGEEWYGKITYIGFEENIKDPADVEKKIREAQNKIAGPGSGISEDLISLEIASPDVPDLTLIDLPGIARVAVKGQPENIGDQIKRLIQKFITKQETISLVVVPCNVDIATTEALNMAQRVDPDGERTLGILTKPDLVDKGTEETVVDIVHNEVIHLKKGYMIVKCRGQKEITEKVSLTEAIEREKAFFNDHVFFHTLYNDGHATVPKLAEKLTLELVHHIEKSLPRLEEQIEKKLIETQVELNKYGNGPPPDTSERLGFLIDRVTAFTQDAISLTSGEELKSGVRLNIFSMLRKEFAAWKEMIERSGVTFNWNIEKEVAQYERKYRGRELPGFINYKTFEVMVPGFVNYKTFEGMVKEQIKQLEEPAVLKLKEVAEIVKKELFKVAQNSFVGFPNLMRAAKMMIEAIRKEKEIVAESMLRTQFKMESIVYTQDSTYSKKLGKRKREDLQDGVTGLGTQVKLNTSSTVGNNGTGATLKEMLKHLKSYYQIAGQRLADQIPLVIRYQMLQESAVQLQREMLQMLQDKEKNKVLLHEDSGITNKRIHLQKRLERLSKARLLLTDFSMNIYNFNTTQL |
Expression
Induction
By interferons.
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 30-303 | Dynamin-type G | ||||
Sequence: DLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLELKMKRKNEGEEWYGKITYIGFEENIKDPADVEKKIREAQNKIAGPGSGISEDLISLEIASPDVPDLTLIDLPGIARVAVKGQPENIGDQIKRLIQKFITKQETISLVVVPCNVDIATTEALNMAQRVDPDGERTLGILTKPDLVDKGTEETVVDIVHNEVIHLKKGYMIVKCRGQKEITEKVSLTEAIEREKAFFNDHVFFHTLYNDGHATVPKLAEKLTLELVHHIEKSLP | ||||||
Region | 40-47 | G1 motif | ||||
Sequence: GDQSSGKS | ||||||
Region | 65-67 | G2 motif | ||||
Sequence: VTR | ||||||
Region | 141-144 | G3 motif | ||||
Sequence: DLPG | ||||||
Region | 210-213 | G4 motif | ||||
Sequence: TKPD | ||||||
Region | 242-245 | G5 motif | ||||
Sequence: KCRG | ||||||
Domain | 554-645 | GED | ||||
Sequence: LKEMLKHLKSYYQIAGQRLADQIPLVIRYQMLQESAVQLQREMLQMLQDKEKNKVLLHEDSGITNKRIHLQKRLERLSKARLLLTDFSMNIY |
Sequence similarities
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length652
- Mass (Da)73,824
- Last updated2007-03-06 v2
- Checksum1AB527A8B52EB2A1
Keywords
- Technical term