Q2GUU0 · YME2_CHAGB
- ProteinMitochondrial escape protein 2
- GeneYME2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids831 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA (By similarity).
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | RNA binding | |
Biological Process | mitochondrial genome maintenance | |
Biological Process | mRNA processing |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameMitochondrial escape protein 2
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Sordariomycetidae > Sordariales > Chaetomiaceae > Chaetomium
Accessions
- Primary accessionQ2GUU0
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Single-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 49-301 | Mitochondrial matrix | ||||
Sequence: ESTSGAVGSDNSGHIDTQPNESILFFDNIFPLKLSSVLLWRAWETNELLRRFNSASLSFLDPIGLVKRAIPESAPIKVTEIIPRLKEGGAYVKFTYPDSISPADIEDQLVKYHEKTPIKPWFNPFRTIKSRLVLGRPWLEDLYRLPKSRLKIEFVPAKNSEPPTELSQESLYSLFRRYGKISDITSQAPDSKVLPKFAYVDFVLVRDAILARNCIHGFVLQEEGSKSLTRLRLSYEQRVKAHHIWNWVTGHPR | ||||||
Transmembrane | 302-322 | Helical | ||||
Sequence: IVIPVIAAFLAAFTVAVFDPI | ||||||
Topological domain | 323-831 | Mitochondrial intermembrane | ||||
Sequence: REFFVKRQTSDILAFRKRGDDDAGLSALFTHRKDLIDSIQNNLLETVGTFIVVQGPRGSGGRELVMDQVLEGRRDVLVVDCRQVVEARGEAGTIRKLANQVGYRPVFSWANNLSSMVDLAIQSTTGVKAGFSENLESQVTKILQTTAEALKDVSLARRKRDKDANLTDDAYLEAHPERRPVIVIDNFLHKSEEKGIVYDKISDWASALVQANIAHVIFLTTDTSYSKPLSKALPDRVFHQITLGDLTPEVAKHFVVSQLETDEDADEKKNGASPAISERKLRRDLQELDECIDALGGRLTDLQVLARRLKVGQSPKKAVSDIIDQSASEILRMFLLTNKGAGSGDKKWSTEQAWYLIKQIASKESLRYNEVLLSDTFASSTTADASNAEAALESLANAELVTIKSHHGRPATIRAGKPVYQAAFNRLLDDAVVNARMDLAVLTELAKIEAKKIDKAEGELSVLGSLPSQPYQTADRVNYLLAKLQGSQEKIVAYEKEMAGLKKVLSEEA |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for transit peptide, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transit peptide | 1-48 | Mitochondrion | ||||
Sequence: MISGRVLYRPAGRRGVGPLPLAATTYALRRRSPSITALGQPRRLIRRW | ||||||
Chain | PRO_0000343119 | 49-831 | Mitochondrial escape protein 2 | |||
Sequence: ESTSGAVGSDNSGHIDTQPNESILFFDNIFPLKLSSVLLWRAWETNELLRRFNSASLSFLDPIGLVKRAIPESAPIKVTEIIPRLKEGGAYVKFTYPDSISPADIEDQLVKYHEKTPIKPWFNPFRTIKSRLVLGRPWLEDLYRLPKSRLKIEFVPAKNSEPPTELSQESLYSLFRRYGKISDITSQAPDSKVLPKFAYVDFVLVRDAILARNCIHGFVLQEEGSKSLTRLRLSYEQRVKAHHIWNWVTGHPRIVIPVIAAFLAAFTVAVFDPIREFFVKRQTSDILAFRKRGDDDAGLSALFTHRKDLIDSIQNNLLETVGTFIVVQGPRGSGGRELVMDQVLEGRRDVLVVDCRQVVEARGEAGTIRKLANQVGYRPVFSWANNLSSMVDLAIQSTTGVKAGFSENLESQVTKILQTTAEALKDVSLARRKRDKDANLTDDAYLEAHPERRPVIVIDNFLHKSEEKGIVYDKISDWASALVQANIAHVIFLTTDTSYSKPLSKALPDRVFHQITLGDLTPEVAKHFVVSQLETDEDADEKKNGASPAISERKLRRDLQELDECIDALGGRLTDLQVLARRLKVGQSPKKAVSDIIDQSASEILRMFLLTNKGAGSGDKKWSTEQAWYLIKQIASKESLRYNEVLLSDTFASSTTADASNAEAALESLANAELVTIKSHHGRPATIRAGKPVYQAAFNRLLDDAVVNARMDLAVLTELAKIEAKKIDKAEGELSVLGSLPSQPYQTADRVNYLLAKLQGSQEKIVAYEKEMAGLKKVLSEEA |
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 196-286 | RRM | ||||
Sequence: SRLKIEFVPAKNSEPPTELSQESLYSLFRRYGKISDITSQAPDSKVLPKFAYVDFVLVRDAILARNCIHGFVLQEEGSKSLTRLRLSYEQR |
Sequence similarities
Belongs to the YME2 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length831
- Mass (Da)92,715
- Last updated2006-03-21 v1
- Checksum9D8307B14AC2343A
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CH408033 EMBL· GenBank· DDBJ | EAQ87011.1 EMBL· GenBank· DDBJ | Genomic DNA |