Q2G8K8 · PYRH_NOVAD

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site16-19ATP (UniProtKB | ChEBI)
Binding site58UMP (UniProtKB | ChEBI)
Binding site59ATP (UniProtKB | ChEBI)
Binding site63ATP (UniProtKB | ChEBI)
Binding site78UMP (UniProtKB | ChEBI)
Binding site139-146UMP (UniProtKB | ChEBI)
Binding site166ATP (UniProtKB | ChEBI)
Binding site172ATP (UniProtKB | ChEBI)
Binding site175ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • Ordered locus names
      Saro_1371

Organism names

Accessions

  • Primary accession
    Q2G8K8

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000539681-244Uridylate kinase

Interaction

Subunit

Homohexamer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the UMP kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    244
  • Mass (Da)
    26,248
  • Last updated
    2006-03-21 v1
  • Checksum
    FAF42119402C389F
MSLPSCVPGYRRILLKLSGEVLMGEQQFGIDTDYVARVAQEVKDARDSGLEICLVIGGGNIFRGMAGAAKGMDRAQADYMGMLATVMNALAMQSALEQLGVPTRVQSAIEMDKVCEPVIRRRAERHLEKGRIVIFAAGVGAPYFTTDSGAALRAAEMKCDALLKGTSVDGVYNADPKKDPAAKRYETVDYDTVLADNLKVMDASAVALCRDNNIPIVVFSIRERGNLARVLAGEGTQTTVKKEA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000248
EMBL· GenBank· DDBJ
ABD25815.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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