Q1MPZ9 · FTHS_LAWIP

Function

Catalytic activity

Pathway

One-carbon metabolism; tetrahydrofolate interconversion.

Features

Showing features for binding site.

159150100150200250300350400450500550
TypeIDPosition(s)Description
Binding site74-81ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionATP binding
Molecular Functionformate-tetrahydrofolate ligase activity
Biological Processtetrahydrofolate interconversion

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Formate--tetrahydrofolate ligase
  • EC number
  • Alternative names
    • Formyltetrahydrofolate synthetase
      (FHS
      ; FTHFS
      )

Gene names

    • Name
      fhs
    • Ordered locus names
      LI0874

Organism names

Accessions

  • Primary accession
    Q1MPZ9

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002930441-591Formate--tetrahydrofolate ligase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the formate--tetrahydrofolate ligase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    591
  • Mass (Da)
    64,251
  • Last updated
    2006-05-30 v1
  • Checksum
    C08387A37F820458
MSLSPLNYADWEIAQAAEKHMKTVYDLGKDLGLDHKEIFPYGHYMGKVDYKSVLSRLEQSSDGKYIDVTAITPTPLGEGKSTTTIGLVQGLAKRGKRSSAAIRQPSGGPTMGVKGSAAGGGLSQCIPLTQYSLGFTGDINAVMNAHNLSMVALTSRMQHERNYSDEKLYALSNMKRLDIDPTNIPMGWVMDFCCQSLRNIIIGIDGVSGKSDGYMMRSHFDIAVSSEVMAILAIAKDLKDFRQRISKIIVAYDKQGKAITTADLEVDGAMTAWMVEAINPNLIQSIEGQPIFVHAGPFANIAIGQSSVIADRLGLKLSEYHVTESGFGVDIGYEKFWNLKCHYSGLTPDAAVIVTTVRALKSHGGAPIPIPGRPLPKEYTEENVGYVEVGSANLIHHINTVKKSGVPPVVCINAFTTDTPSEIAKIRQLCELVGARVAVSKHWEYGGDGALELADAVIDACNEEKNFLPLYDWSLPLKERIEKIAFEVYGAEGVEFSEEAIYKLNKLQADNNSSDLGVCMVKTHLSLSDDPKQKGVPDHWKLHVRDIMFFGGAGFVVPIAGSITLMPGTGSNPSFRRIDVDTDTGKVKGIF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AM180252
EMBL· GenBank· DDBJ
CAJ54928.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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