Q1DHP3 · SEC16_COCIM

Function

function

Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum exit site
Cellular Componentendoplasmic reticulum membrane
Cellular ComponentER to Golgi transport vesicle membrane
Biological Processautophagy
Biological ProcessCOPII vesicle coating
Biological ProcessGolgi organization
Biological Processprotein localization to endoplasmic reticulum exit site
Biological Processprotein transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    COPII coat assembly protein SEC16
  • Alternative names
    • Protein transport protein SEC16

Gene names

    • Name
      SEC16
    • ORF names
      CIMG_10170

Organism names

Accessions

  • Primary accession
    Q1DHP3
  • Secondary accessions
    • J0HH29

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002955351-1717COPII coat assembly protein SEC16

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region209-253Disordered
Compositional bias211-225Polar residues
Compositional bias235-253Polar residues
Region290-339Disordered
Compositional bias315-329Basic and acidic residues
Compositional bias382-406Polar residues
Region382-722Disordered
Compositional bias418-444Polar residues
Compositional bias473-492Polar residues
Compositional bias495-510Pro residues
Compositional bias535-553Polar residues
Compositional bias569-584Polar residues
Compositional bias587-624Pro residues
Compositional bias626-666Polar residues
Compositional bias682-722Polar residues
Region1260-1505Disordered
Compositional bias1302-1367Polar residues
Compositional bias1448-1479Polar residues
Compositional bias1480-1505Basic and acidic residues
Region1529-1564Disordered
Region1582-1717Disordered
Compositional bias1602-1622Polar residues
Compositional bias1630-1653Pro residues
Compositional bias1673-1689Polar residues

Sequence similarities

Belongs to the SEC16 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,717
  • Mass (Da)
    184,836
  • Last updated
    2006-07-11 v1
  • Checksum
    5B43B3E930494CFA
MAEDRVLGHESGLFTDAIHLGAWNPAHRPEDFSDSVLHEVATQTSVPIQTPDLAPCPPTEFELEHRDPEASPPDNVLDETKDVEYLQAFPEAPTRLENSGHVDITGSEYMQSIEKTREGAVIDSNNGSPFIDSFKGSDDDTGTNTFPDDNIDFQAMIGQTHDDTRDVWDRSTDAHVEDLSTQLVTEPYSAENDKVNSWNSVFADDEGGGDFFSQISSQSKPTVAHLESEPRSDDMASHLSNGNVQPSNESQQTKAIDSLFQEDESTGEADFFNSQGPAHVEPSLELLSETQPNSMPEDHPLPSLDPGKELPHHQSVAVVQDEKPEVIRPAEPGVAENLGEEELAERWKAFLGDDDILIENETLDGSIEGANTHTAEYQRHPVQPASQVGSEQPPVNTYTPHQPSSSEMLGGLPAAGYSSTLGNLTNPEKSKVESFSNQSKAGYQSPYDLPFDMRPKHAPPRKIAPPVGVNPPPRSSSMSGSRPPSSSYMVPGPNFSPVAAPPPVSGPDTTPPSTKEPVRTGSFFEELPVVSRSRPSTRGRYTPQPNMSQPASNLPMAPVAPPPSLPQQSSDPYSQFQLQPPARLDPYSNLSAPPPQPAPTTSRYSPQPPPPGTKPAPFPRYSPAPPQSACMTSSATYVSQSPTVQSSVNALPFQPRTSSPLAQHETAKSYPSPPRKRGSLPVTSIIPTSSVPQFGSDSQIVPPKRSMTQSPGRMMPLQSSVASNQNAYVRPASAHGSKSSIQAPLLQSAYAPAANNRPTQALDFVVPTDGQEHDPLERWKGAPIFKFGFGGTLLSTFPKHIPRYATGQMTPRIKPTLGDIKTCPISQILPHNEPLDKFPGPLKSKSKKKDVLTWLSTMISALEGAPSTTDGHVDPVHQHRREDGILLWKVVRVLVEHDGALRGSTAAEASLQSIFSPGSMAMNSQFEYPSTGDSVSGSLKSESASSLGIDVIHKSLVAGDRQKAVWDAVDHRLWGHAMLISSTLDKSVWKQVTQEFIRREVRSLGKNTESLAALYEIFAGNFEESIDELVPPSARAGLQMVSVHAGTGAPKDALEGLNKWRDTVNLILQNKIAQDHQALRALGRLLASYGRVEASHICSLVAGTAAGPIFGDARDPQASIVLLGADHWRNPTTFMVEREACLLTEVYEFATSVLAASPSPSLAHLQAFKLRHAMYLAEEGHKSEAQQYCEAIVSIVTSKSNVKSPYYHQRFFAELDELSHRLRQAPTDGSSSWISKPSMEKVSGSMWAKFNSFVSGDDNEVTSNGSGKGGDGDIGPFAKIAGTPPISRSPSVAEGHGSYFPSQPVAPSSSGSRYAPNSQYYAPYSSPEQSRGRRSLDAQRSPPQTAGRSYSQRRNSQDPSTPLEGNAYGSMPNHIYASPATIGSHITPPQASHAPLAPVEEIYSPQIQSPTSEMPAIQTLPDGFGINQTGYMPLAEQVTRDDETNLKTTTTEQSGYQPPTYEPPSFSTGYEPPSYSANVEDNEHSDEEKPKKKSFMDDDDDDFMARAAQLRASEKEKMDREAAEAFRKAAEADAKRPLATEKKGWFSGWFGKKESGGAVRADLGDENSFYFDKELNRWVNKKDPGSAATAAVTPPPPKSSAPSSQSVSTSQTPTTPNLTNGRPGPSAVPGGTLSAPPPGIAPLPTPPSSSLGPPSDSPRAIPRSVSAGAPTGPPSRPGTSLSNASSIDDLLGAPQARKGGTMKTRRKGRGYVDVMAK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias211-225Polar residues
Compositional bias235-253Polar residues
Compositional bias315-329Basic and acidic residues
Compositional bias382-406Polar residues
Compositional bias418-444Polar residues
Compositional bias473-492Polar residues
Compositional bias495-510Pro residues
Compositional bias535-553Polar residues
Compositional bias569-584Polar residues
Compositional bias587-624Pro residues
Compositional bias626-666Polar residues
Compositional bias682-722Polar residues
Compositional bias1302-1367Polar residues
Compositional bias1448-1479Polar residues
Compositional bias1480-1505Basic and acidic residues
Compositional bias1602-1622Polar residues
Compositional bias1630-1653Pro residues
Compositional bias1673-1689Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GG704915
EMBL· GenBank· DDBJ
EAS27565.3
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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