Q0QHL3 · CISY_GLOMM
- ProteinProbable citrate synthase, mitochondrial
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids465 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Miscellaneous
Citrate synthase is found in nearly all cells capable of oxidative metabolism.
Catalytic activity
- oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H+
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 303 | |||||
Sequence: H | ||||||
Active site | 349 | |||||
Sequence: H | ||||||
Active site | 404 | |||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial matrix | |
Molecular Function | citrate (Si)-synthase activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | citrate metabolic process | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable citrate synthase, mitochondrial
- EC number
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Hippoboscoidea > Glossinidae > Glossina
Accessions
- Primary accessionQ0QHL3
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain, transit peptide.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000291557 | ?-465 | Probable citrate synthase, mitochondrial | |||
Sequence: MSIYRISTTRKMPEVQKLNALLASYVRFISADSSLRDVLAAKIPAEQERVKNFRKQHGSFKMGETTVDMMYGGMRGIKALVTETSVLDADEGIRFRGLSIPECQKVLPAADGGEEPLPEGLFWLLLTGEVPSKAQVKQVSREWAARAALPQHVVTMLNNFPTSLHPMSQFSAAITALNHDSKFAKAYSDGVHKSKYWEHVYEDSMDLIAKLPVVAATIYCNTYRNGKGSKSIDSSLDWSANFVKMLGYDDPKFTELMRLYLTIHSDHEGGNVSAHTVHLVGSALSDPYLSFAAGMNGLAGPLHGLANQEVLVWLRKLQKEAGSNPSEEQLKEYIWKTLKSGQVVPGYGHAVLRKTDPRYTCQREFALKHLPNDELFQLVSKIYKVVPPILQETGKVKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVSRALGVLASLVWDRALGLPIERPKSLSTDLLMKMVQK | ||||||
Transit peptide | 1-? | Mitochondrion |
Interaction
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length465
- Mass (Da)51,864
- Last updated2006-09-05 v1
- Checksum8584A6B0BA0E84C6