Q0HM20 · RLMC_SHESM

  • Protein
    23S rRNA (uracil(747)-C(5))-methyltransferase RlmC
  • Gene
    rlmC
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

Catalytic activity

Features

Showing features for binding site, active site.

138450100150200250300350
TypeIDPosition(s)Description
Binding site7[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site15[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site18[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site94[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site219S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site248S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site269S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site316S-adenosyl-L-methionine (UniProtKB | ChEBI)
Active site343Nucleophile

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functioniron ion binding
Molecular FunctionrRNA (uridine-C5-)-methyltransferase activity
Biological ProcessrRNA base methylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    23S rRNA (uracil(747)-C(5))-methyltransferase RlmC
  • EC number
  • Alternative names
    • 23S rRNA(m5U747)-methyltransferase

Gene names

    • Name
      rlmC
    • Synonyms
      rumB
    • Ordered locus names
      Shewmr4_0817

Organism names

Accessions

  • Primary accession
    Q0HM20

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002820151-38423S rRNA (uracil747-C5)-methyltransferase RlmC

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    384
  • Mass (Da)
    42,641
  • Last updated
    2006-10-03 v1
  • Checksum
    13EC610ABAE336AD
MSTLVQCGYFERGQCQSCRHIKLPMAQQLAAKTQELQQLLAPFVDNAEPQFLPPVVGDSSGFRNKAKMVALGAAHAPVLGIVSPSGEAVSLCDCLLYPADMQALLHRLERFVQQAGIPPYRVDKAKGELKFILLTRSQVRGEYMLRFVLRSRDAIARIERELPALMAEYPQIKVVSVNLQPVHMAILEGEEEIFLTENTRLEERFNDVPLFIRPKSFFQTNPQVAAKLYQTAREWVADFAPASLWDLFCGVGGFGLHCAAKDIPLTGIEIEAEAIACAKMSAQLMGLDKVQFMALDSTDFAKGDAAQTKPELIIVNPPRRGIGESLCHSLSEFAPKAILYSSCNPKTLAKDLGHIRGYRLTKVQLFDLFPHSDHFEVLALLVKD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000446
EMBL· GenBank· DDBJ
ABI37897.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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