Q07957 · USF1_XENBO

Function

function

May act as a regulator of transcription factor IIIA (TFIIIA) gene expression.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Functionprotein dimerization activity
Molecular FunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Upstream stimulatory factor 1
  • Short names
    USF
  • Alternative names
    • B1 factor
    • SPF1

Gene names

    • Name
      usf1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus

Accessions

  • Primary accession
    Q07957

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001274991-307Upstream stimulatory factor 1

Expression

Tissue specificity

Oocyte and somatic tissue. Oocytic and somatic forms of this protein exist, probably as a result of post-translational modifications or minor splicing differences.

Developmental stage

In the oocyte, the protein accumulates from stage 1 to stage 5/6 of oogenesis and persists through gastrulation while the somatic protein begins to accumulate at early cleavage and, by the neurula stage, is the dominant, if not exclusive, form present.

Interaction

Subunit

Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a homodimer or a heterodimer.

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region104-131Disordered
Region168-207Disordered
Compositional bias187-207Basic and acidic residues
Domain196-251bHLH
Region268-289Leucine-zipper

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    307
  • Mass (Da)
    33,565
  • Last updated
    1996-11-01 v1
  • Checksum
    FACA6C08F1C4CEE5
MKGQQKVADIEEGTVRVQEEGAVATGEDPTSVAIASIQSAATFSDPNVKYVFRTENGGAQVMYRVIQVAEGQLDGQTEGTGAISGFPATQSMTQAVIQGAFTSDDNGETDASGPETHYTYFPTDSSTSVGGTPTTVVTTHNSDTLLGQAASTGTGQFYVMMSSQDVLQGGSQRSIAPRTHPYSPKSDGPRTTRDDKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKTGQSKGGILSKACDYIQELRQSNLRLSEELQNLDQLQMDNEVLRQQVEDLKNNNLTLRTQLRHHGVEIIIKSDTH

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias187-207Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M63663
EMBL· GenBank· DDBJ
AAA49651.1
EMBL· GenBank· DDBJ
mRNA
M63664
EMBL· GenBank· DDBJ
AAA49652.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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