Q06576 · HP25_TAMSI

Function

function

Plasma proteins HP-20, HP-25, HP-27 and HP-55 form a 140 kDa complex via disulfide bonds in the plasma and are hibernation specific.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcollagen trimer
Cellular Componentextracellular region
Biological Processhibernation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Hibernation-associated plasma protein HP-25
  • Alternative names
    • Hibernator-specific blood complex 25 kDa subunit

Organism names

Accessions

  • Primary accession
    Q06576

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation.

TypeIDPosition(s)Description
Signal1-28
ChainPRO_000000355929-215Hibernation-associated plasma protein HP-25
Glycosylation167N-linked (GlcNAc...) asparagine

Keywords

Expression

Tissue specificity

Plasma; synthesized in the liver.

Developmental stage

The protein complex disappears from the plasma at onset of hibernation and reappears as hibernation ceases.

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region29-96Disordered
Compositional bias38-76Pro residues
Domain40-81Collagen-like
Domain85-215C1q

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    215
  • Mass (Da)
    22,664
  • Last updated
    1995-11-01 v1
  • Checksum
    AFE03206917EA530
MPAQRGGALSMGAAGFWILVLSITSALADSNNQGNSEPCGPPGPPGPPGIPGFPGAPGALGPPGPPGVPGIPGPQGPPGDVEKCSSRPKSAFAVKLSERPPEPFQPIVFKEALYNQEGHFNMATGEFSCVLPGVYNFGFDIRLFQSSVKIRLMRDGIQVREKEAQANDSYKHAMGSVIMALGKGDKVWLESKLKGTESEKGITHIVFFGYLLYGK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias38-76Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
D12975
EMBL· GenBank· DDBJ
BAA02352.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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