Q00384 · ALKH_ZYMMO
- ProteinKHG/KDPG aldolase
- Geneeda
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids208 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
Catalytic activity
- (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate
Pathway
Carbohydrate acid metabolism; 2-dehydro-3-deoxy-D-gluconate degradation; D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-gluconate: step 2/2.
Carbohydrate metabolism; glyoxylate and dicarboxylate metabolism.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 41 | |||||
Sequence: E | ||||||
Active site | 45 | |||||
Sequence: R | ||||||
Active site | 128 | Schiff-base intermediate with KHG or pyruvate | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | (4S)-4-hydroxy-2-oxoglutarate aldolase activity | |
Molecular Function | 2-dehydro-3-deoxy-phosphogluconate aldolase activity | |
Molecular Function | 4-hydroxy-2-oxoglutarate aldolase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameKHG/KDPG aldolase
Including 2 domains:
- Recommended name4-hydroxy-2-oxoglutarate aldolase
- EC number
- Alternative names
- Recommended name2-dehydro-3-deoxy-phosphogluconate aldolase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Zymomonadaceae > Zymomonas
Accessions
- Primary accessionQ00384
- Secondary accessions
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000201044 | 1-208 | KHG/KDPG aldolase | |||
Sequence: MRDIDSVMRLAPVMPVLVIEDIADAKPIAEALVAGGLNVLEVTLRTPCALEAIKIMKEVPGAVVGAGTVLNAKMLDQAQEAGCEFFVSPGLTADLGKHAVAQKAALLPGVANAADVMLGLDLGLDRFKFFPAENIGGLPALKSMASVFRQVRFCPTGGITPTSAPKYLENPSILCVGGSWVVPAGKPDVAKITALAKEASAFKRAAVA |
Interaction
Structure
Sequence
- Sequence statusComplete
- Length208
- Mass (Da)21,505
- Last updated2005-02-15 v2
- Checksum1685B45A7DFB57B4
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 1-4 | in Ref. 1; CAA41258 | ||||
Sequence: MRDI → M |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X58364 EMBL· GenBank· DDBJ | CAA41258.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE008692 EMBL· GenBank· DDBJ | AAV89621.1 EMBL· GenBank· DDBJ | Genomic DNA |