P71153 · ETFA_THETC

Function

function

The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Note: Binds 1 FAD per dimer.

Features

Showing features for binding site.

133050100150200250300
TypeIDPosition(s)Description
Binding site270-298FAD (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionelectron transfer activity
Molecular Functionflavin adenine dinucleotide binding
Biological Processfatty acid beta-oxidation using acyl-CoA dehydrogenase

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Electron transfer flavoprotein subunit alpha
  • Short names
    Alpha-ETF
  • Alternative names
    • Electron transfer flavoprotein large subunit (ETFLS)

Gene names

    • Name
      etfA
    • Ordered locus names
      Tthe_1658

Organism names

Accessions

  • Primary accession
    P71153
  • Secondary accessions
    • D9TPZ8
    • O08252

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001678491-330Electron transfer flavoprotein subunit alpha

Interaction

Subunit

Heterodimer of an alpha and a beta subunit.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the ETF alpha-subunit/FixB family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    330
  • Mass (Da)
    35,555
  • Last updated
    2010-11-30 v2
  • Checksum
    DDE0F20FDA14B681
MNDYKDIWIFAEQRNGKLMNVAIEILGEARKLADKKGVNVGAVLIGHNVENLSKDLISFGADIVYVVDNPLLSNYTTEGYAKAISELAKEYKPEVILYGATFIGRDLAPRIASRLMTGLTADCTGLDIDENGLLLQTRPAFGGNLMATIKCPDKRPQMSTVRPGVMKRAIRDDTRDGKVIKFDADINESDIRTKILSIAKEAKNVVNLEEADIIVSGGRGIGGPDGFNIIKELADVLGGVVGASRATVDAGWITSDHQVGQTGKTVRPKLYIACGISGAIQHLAGMSNSGTIVAINKNPDAPIFKFADYGIVGDLFKVIPVLIEEIKKLK

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict166-176in Ref. 1; CAB04791/CAB07498
Sequence conflict237in Ref. 1; CAB04791/CAB07498

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z82038
EMBL· GenBank· DDBJ
CAB04791.1
EMBL· GenBank· DDBJ
Genomic DNA
Z92974
EMBL· GenBank· DDBJ
CAB07498.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002171
EMBL· GenBank· DDBJ
ADL69167.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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