P56630 · CYB_ASPFM

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Miscellaneous

Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.

Caution

The protein contains only eight transmembrane helices, not nine as predicted by bioinformatics tools.

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme b groups non-covalently.

Features

Showing features for binding site.

114520406080100120140
TypeIDPosition(s)Description
Binding site42Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site56Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site61a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial respiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b
  • Alternative names
    • Complex III subunit 3
    • Complex III subunit III
    • Cytochrome b-c1 complex subunit 3
    • Ubiquinol-cytochrome-c reductase complex cytochrome b subunit

Gene names

    • Name
      cob
    • Synonyms
      cytB

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strains
    • IFM 40804
    • IFM 40806
    • IFM 40807
    • IFM 40819
    • IFM 41206
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Fumigati

Accessions

  • Primary accession
    P56630

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane38-58Helical
Transmembrane85-105Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000617361-145Cytochrome b

Interaction

Subunit

Fungal cytochrome b-c1 complex contains 10 subunits; 3 respiratory subunits, 2 core proteins and 5 low-molecular weight proteins. Cytochrome b-c1 complex is a homodimer.

Structure

Family & Domains

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    145
  • Mass (Da)
    16,295
  • Last updated
    1998-12-15 v1
  • Checksum
    376A89A0C8F6FA7D
WGATVITNLMSAIPWIGQDIVEFIWGGFSVNNATLNRFFALHFLLPFVLAALVIMHLIAMHDTVGSGNPLGISGNYDRLPFAPYFVFKDLVTVFIFFIVLSVFVFFMPNALGDSENYVMANPMQTPPAIVPEWYLLPFYAILRSI

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue145

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB000566
EMBL· GenBank· DDBJ
BAA34133.2
EMBL· GenBank· DDBJ
Genomic DNA
AB000567
EMBL· GenBank· DDBJ
BAA34134.2
EMBL· GenBank· DDBJ
Genomic DNA
AB000586
EMBL· GenBank· DDBJ
BAA34151.1
EMBL· GenBank· DDBJ
Genomic DNA
AB000587
EMBL· GenBank· DDBJ
BAA34152.1
EMBL· GenBank· DDBJ
Genomic DNA
AB000588
EMBL· GenBank· DDBJ
BAA34153.1
EMBL· GenBank· DDBJ
Genomic DNA
AB000589
EMBL· GenBank· DDBJ
BAA34154.1
EMBL· GenBank· DDBJ
Genomic DNA
AB000590
EMBL· GenBank· DDBJ
BAA34155.1
EMBL· GenBank· DDBJ
Genomic DNA
AB000591
EMBL· GenBank· DDBJ
BAA34156.1
EMBL· GenBank· DDBJ
Genomic DNA
AB000592
EMBL· GenBank· DDBJ
BAA34157.1
EMBL· GenBank· DDBJ
Genomic DNA
AB000593
EMBL· GenBank· DDBJ
BAA34158.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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