P23134 · CYB_RHORU
- ProteinCytochrome b
- GenepetB
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids405 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
Miscellaneous
Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.
Cofactor
Note: Binds 2 heme b groups non-covalently.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 94 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 108 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 195 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 209 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Cellular Component | respiratory chain complex III | |
Molecular Function | metal ion binding | |
Molecular Function | ubiquinol-cytochrome-c reductase activity | |
Biological Process | respiratory electron transport chain |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCytochrome b
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Rhodospirillaceae > Rhodospirillum
Accessions
- Primary accessionP23134
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 44-64 | Helical | ||||
Sequence: FGSLAGIAMIIMIATGIFLAM | ||||||
Transmembrane | 97-117 | Helical | ||||
Sequence: GASMFFIVVYVHMFRGLYYGS | ||||||
Transmembrane | 124-144 | Helical | ||||
Sequence: VLWWLGLVILLLMMATAFMGY | ||||||
Transmembrane | 163-183 | Helical | ||||
Sequence: FSAIPVVGDDIVTLLWGGFSV | ||||||
Transmembrane | 191-211 | Helical | ||||
Sequence: FFSLHYLFPMLLFAVVFLHMW | ||||||
Transmembrane | 245-265 | Helical | ||||
Sequence: FGLGIFLMVFCFFVFFAPNFF | ||||||
Transmembrane | 303-323 | Helical | ||||
Sequence: LGGVLAMFGAILILFVLPWLD | ||||||
Transmembrane | 338-358 | Helical | ||||
Sequence: GFFWVFLADCLLLGYLGAMPA | ||||||
Transmembrane | 368-388 | Helical | ||||
Sequence: LATIYYFLHFLVITPLVGWFE |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000061773 | 1-405 | Cytochrome b | |||
Sequence: MYTPPRWNNKALKWFDERLPVLTVAHKELVVYPAPRNLNYFWNFGSLAGIAMIIMIATGIFLAMSYTAHVDHAFDSVERIMRDVNYGWLMRYMHANGASMFFIVVYVHMFRGLYYGSYKPPREVLWWLGLVILLLMMATAFMGYVLPWGQMSFWGATVITNLFSAIPVVGDDIVTLLWGGFSVDNPTLNRFFSLHYLFPMLLFAVVFLHMWALHVKKSNNPLGIDAKGPFDTIPFHPYYTVKDAFGLGIFLMVFCFFVFFAPNFFGEPDNYIPANPMVTPTHIVPEWYFLPFYAILRAVPDKLGGVLAMFGAILILFVLPWLDTSKVRSATFRPVFKGFFWVFLADCLLLGYLGAMPAEEPYVTITQLATIYYFLHFLVITPLVGWFEKPKPLPVSISSPVTTQA |
Interaction
Subunit
The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.
Structure
Sequence
- Sequence statusComplete
- Length405
- Mass (Da)46,369
- Last updated1991-11-01 v1
- ChecksumF19452FDA318BE6F
Keywords
- Technical term