P21921 · COBL_SINSX
- ProteinPrecorrin-6Y C(5,15)-methyltransferase [decarboxylating]
- GenecobL
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids413 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X.
Catalytic activity
- precorrin-6B + 2 S-adenosyl-L-methionine = CO2 + 3 H+ + precorrin-8X + 2 S-adenosyl-L-homocysteine
Pathway
Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 7/10.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | precorrin-6Y C5,15-methyltransferase (decarboxylating) activity | |
Molecular Function | protein methyltransferase activity | |
Biological Process | cobalamin biosynthetic process | |
Biological Process | methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePrecorrin-6Y C(5,15)-methyltransferase [decarboxylating]
- EC number
- Short namesPrecorrin-6 methyltransferase; Precorrin-6Y methylase
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Sinorhizobium/Ensifer group > Sinorhizobium
Accessions
- Primary accessionP21921
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000150408 | 1-413 | Precorrin-6Y C(5,15)-methyltransferase [decarboxylating] | |||
Sequence: MADVSNSEPAIVSPWLTVIGIGEDGVAGLGDEAKRLIAEAPVVYGGHRHLELAASLITGEAHNWLSPLERSVVEIVARRGSPVVVLASGDPFFFGVGVTLARRIASAEIRTLPAPSSISLAASRLGWALQDATLVSVHGRPLDLVRPHLHPGARVLTLTSDGAGPRDLAELLVSSGFGQSRLTVLEALGGAGERVTTQIAARFMLGLVHPLNVCAIEVAADEGARILPLAAGRDDALFEHDGQITKREVRALTLSALAPRKGELLWDIGGGSGSIGIEWMLADPTMQAITIEVEPERAARIGRNATMFGVPGLTVVEGEAPAALAGLPQPDAIFIGGGGSEDGVMEAAIEALKSGGRLVANAVTTDMEAVLLDHHARLGGSLIRIDIARAGPIGGMTGWKPAMPVTQWSWTKG |
Structure
Sequence
- Sequence statusComplete
- Length413
- Mass (Da)42,938
- Last updated1991-05-01 v1
- ChecksumC78E174A79F94249
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
M59301 EMBL· GenBank· DDBJ | AAA25800.1 EMBL· GenBank· DDBJ | Genomic DNA |