P21637 · COBG_SINSX

  • Protein
    Precorrin-3B synthase
  • Gene
    cobG
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the elimination of C-20 in precorrin-3A to form precorrin-3B.

Caution

Was originally thought to originate from Pseudomonas denitrificans, but similarity searches show that the sequence is much closer to Sinorhizobium. The entry's taxonomy has been changed.

Catalytic activity

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 2/10.

Features

Showing features for binding site.

145950100150200250300350400450
TypeIDPosition(s)Description
Binding site338[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site344[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site377[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site381[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site381Fe (UniProtKB | ChEBI) of siroheme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionheme binding
Molecular Functionmetal ion binding
Molecular Functionprecorrin-3B synthase activity
Biological Processcobalamin biosynthetic process
Biological Processporphyrin-containing compound biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • Name
      cobG

Organism names

  • Taxonomic identifier
  • Strain
    • SC510
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Sinorhizobium/Ensifer group > Sinorhizobium

Accessions

  • Primary accession
    P21637

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001999661-459Precorrin-3B synthase

Structure

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    459
  • Mass (Da)
    46,691
  • Last updated
    1996-02-01 v2
  • Checksum
    EC101F4C1FDC7209
MTDLMTSCALPLTGDAGTVASMRRGACPSLAEPMQTGDGLLVRVRPTDDSLTLPKVIALATAAERFGNGIIEITARGNLQLRGLSAASVPRLAQAIGDAEIAIAEGLAIEVPPLAGIDPDEIADPRPIATELREALDVRQVPLKLAPKLSVVIDSGGRFGLGAVVADIRLQAVSTVAGVAWVLSLGGTSTKASSVGTLAGNAVVPALITILEKLASLGTTMRGRDLDPSEIRALCRCETSSERPAAPRSAAIPGIHALGNADTVLGLGLAFAQVEAAALASYLHQVQALGANAIRLAPGHAFFVLGLCPETAAVAQSLAASHGFRIAEQDPRNAIATCAGSKGCASAWMETKGMAERLVETAPELLDGSLTVHLSGCAKGCARPKPSELTLVGAPSGYGLVVNGAANGLPSAYTDENGMGSALARLGRLVRQNKDAGESAQSCLTRLGAARVSAAFEQG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M59301
EMBL· GenBank· DDBJ
AAA25795.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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