P16465 · HLYB_PROMI
- ProteinHemolysin transporter protein HpmB
- GenehpmB
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids561 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Interacts with the cell-bound hemolysin. Necessary for the extracellular secretion and activation of the hemolysin.
Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cell outer membrane | |
Cellular Component | pore complex | |
Cellular Component | type V protein secretion system complex | |
Molecular Function | porin activity | |
Molecular Function | protein transmembrane transporter activity | |
Biological Process | killing of cells of another organism | |
Biological Process | monoatomic ion transport | |
Biological Process | protein secretion by the type V secretion system |
Keywords
- Molecular function
- Biological process
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameHemolysin transporter protein HpmB
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Proteus
Accessions
- Primary accessionP16465
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-17 | |||||
Sequence: MKKKVVLLTLLSCFSTS | ||||||
Chain | PRO_0000018664 | 18-561 | Hemolysin transporter protein HpmB | |||
Sequence: GLSANETGNLGSISESRRALQDSQREINQLIEQNRYQQLQEKAVNISPTPTLITESEHCLPIKGVYIQGITLLTEKDLNSLSPLPDQCIKSADINRLVKELTQRYLQHGYITARIQFLRPNQHGELGLYAIEGFVERIEGGDRGVNTTLLFPRIKGQPLKLATLDQGLDQANRLQSNKVTVDILPGTELGGSVIKLSNQRKSPWHLNIASDNYGQKNSGRWLIRTNASLDSPLGLSDFVSLNANITTDNPNTRFNRAYTLLYSIPYGGFTFSSFGSYSEYQFHQKLQTRTVNLYGDTTQVGIRGDYAFSRSQKQIDTLNIQVTHKRIRNYFSQIRLDLSSPKLTTIELGINHLQIIPNGVLSTNLSVEKAVGWFGAEETPYIANGNGNDYRFTKVKLFTNWYQRFSLWHSTFLFNSTFLGQYSHDTLPGVEWLSLTDKNAIRGFDQSTLSGDNGGYLRNTLSYPYRLNHFSITPRIGVDIGQVKQHGNYKGWQGGYGLSSGLNIQYQQAQLDLEVAKGELLYHQTNSNKTKDPTQLLVKFSYLF |
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 77-150 | POTRA | ||||
Sequence: LPIKGVYIQGITLLTEKDLNSLSPLPDQCIKSADINRLVKELTQRYLQHGYITARIQFLRPNQHGELGLYAIEG |
Domain
Probably a beta-barrel protein.
Sequence similarities
Belongs to the TPS (TC 1.B.20) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length561
- Mass (Da)63,222
- Last updated1990-08-01 v1
- Checksum6849E9C3BAA2891D