P15349 · RPO1N_HALMO

Function

function

DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit Rpo1N
  • EC number
  • Alternative names
    • DNA-directed RNA polymerase subunit A'

Gene names

    • Name
      rpo1N
    • Synonyms
      rpoA1

Organism names

  • Taxonomic identifier
  • Strain
    • ATCC 17082 / DSM 1307 / JCM 8876 / NBRC 14719 / NCIMB 787
  • Taxonomic lineage
    Archaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Halococcaceae > Halococcus

Accessions

  • Primary accession
    P15349

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000740021-349DNA-directed RNA polymerase subunit Rpo1N

Interaction

Subunit

Part of the RNA polymerase complex.

Structure

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region306-349Disordered
Compositional bias322-336Basic and acidic residues

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    349
  • Mass (Da)
    38,074
  • Last updated
    1990-04-01 v1
  • Checksum
    62EEA0E03C5D2ED1
EFTSSTGDTVMIDEGALVEGTIDEDAVGAFGGEIVDTIVKQYGETRARVFINEVASLAMRAIMHFGFSIGIDDESISDAAEAQIDESMDNAYERVQELIDTYENDDLESLPGRTVDETLEMKIMQTLGKARDSAGDIADEHFDDDNPAVIMAESGARGSMLNLTQMAACVGQQAVRGERINRGYEGRTLSHFKPGDLSAEAHGFVEDSYRSGLTPREFFFHAMGGREGLVDTAVRTSKSGYLQRRLINALSELETQYDGTVRDTSDNIVQFEFGEDNTSPVKVSSSDDNEIDVDEIADRVLAAEFEDEGEEFAGEQATNLSESADDRMDRDRPSSHGAAPIDVPEVGDD

Features

Showing features for non-terminal residue, compositional bias, sequence conflict.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias322-336Basic and acidic residues
Sequence conflict336-339in Ref. 1; CAA40431

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X57145
EMBL· GenBank· DDBJ
CAA40431.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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