P0DI96 · OMP2B_BRUSS

  • Protein
    Porin Omp2b
  • Gene
    omp2b
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

function

Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.

Miscellaneous

The pore formed by Omp2a is larger than the one formed by Omp2b. Omp2b pores have optimal permeability to allow growth and protection against harmful compounds. The larger pore formed by Omp2a may be advantageous for intracellular growth, when the bacterium is competing with the host cell for nutrients whose concentration is particularly low within the phagosome.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell outer membrane
Cellular Componentpore complex
Molecular Functionporin activity
Biological Processmonoatomic ion transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Porin Omp2b

Gene names

    • Name
      omp2b

Organism names

  • Taxonomic identifier
  • Strains
    • 686
    • 83-210
    • De12
    • Fr11
    • Fr7
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Brucellaceae > Brucella/Ochrobactrum group > Brucella

Accessions

  • Primary accession
    P0DI96
  • Secondary accessions
    • Q2KMJ8
    • Q2KMJ9
    • Q2KMK0
    • Q2KMK1
    • Q2KMK2

Subcellular Location

Cell outer membrane
; Multi-pass membrane protein

Keywords

Phenotypes & Variants

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variant59-60in strain: Fr7
Natural variant75-77in strain: 686, De12, Fr7, Pt1 and Thomsen
Natural variant80in strain: Fr11 and Wf21
Natural variant85in strain: De12, Fr7, Pt1 and Thomsen
Natural variant91-95in strain: De12, Fr7, Pt1 and Thomsen
Natural variant114-129in strain: 686, De12, Fr7, Fr11, Pt1, Thomsen and Wf21
Natural variant134in strain: 686, De12, Fr7, Fr11, Pt1, Thomsen and Wf21
Natural variant153in strain: 686, De12, Fr7, Fr11, Pt1, Thomsen and Wf21
Natural variant172in strain: 686, De12, Fr7, Fr11, Pt1, Thomsen and Wf21
Natural variant206-222in strain: 686, De12, Fr7, Fr11, Pt1, Thomsen and Wf21
Natural variant258in strain: 686, De12, Fr7, Fr11, Pt1, Thomsen and Wf21
Natural variant339in strain: 686, De12, Fr7, Fr11, Pt1, Thomsen and Wf21
Natural variant349-350in strain: 686, De12, Fr7, Fr11, Pt1, Thomsen and Wf21
Natural variant354-363in strain: 686, De12, Fr7, Fr11, Pt1, Thomsen and Wf21

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 14 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-22
ChainPRO_000041262923-375Porin Omp2b

Interaction

Subunit

Homotrimer.

Family & Domains

Domain

Consists of 16-stranded beta-barrel sheets, with large surface-exposed loops, that form a transmembrane pore at the center of each barrel. The pore is partially ocluded by a peptide loop that folds into the pore lumen.

Sequence similarities

Belongs to the alphaproteobacteria porin family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    375
  • Mass (Da)
    40,569
  • Last updated
    2011-09-21 v1
  • Checksum
    539EB73D9B828DBB
MNIKSLLLGSAAALVAASGAQAADAIVAPEPEAVEYVRVCDAYGAGYFYIPGTETCLRVHGYVRYDVKGGDDVYSGTDRKGWDKSARFALRVSTGSETELGTLKTFTELRFNYSASNSREDGYYGTNSDGTVMQFAYIQLGGLRVGIDESEFQTFTGYLGDVINDDVISAGTYRTGKISYTFTGGNGFSAVIALEQGGDNDGGYTPVFKDSQGREINGRGYQIDGYMPDVVGGLKYAGGWGSIAGVVAYDSVIEEWATKVRGDVNITDQFSVWLQGAYSSAATPDQNYGQWGGDWAVWGGLKYQATQKAAFNLQAAHDDWGKTAVTANVAYELVPGFTITPEVSYTKFSNEWKRELGNDTLDDAWGGIVRFQRSF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF268034
EMBL· GenBank· DDBJ
AAF80105.1
EMBL· GenBank· DDBJ
Genomic DNA
AY903259
EMBL· GenBank· DDBJ
AAX83995.1
EMBL· GenBank· DDBJ
Genomic DNA
AY903260
EMBL· GenBank· DDBJ
AAX83996.1
EMBL· GenBank· DDBJ
Genomic DNA
AY903261
EMBL· GenBank· DDBJ
AAX83997.1
EMBL· GenBank· DDBJ
Genomic DNA
AY903262
EMBL· GenBank· DDBJ
AAX83998.1
EMBL· GenBank· DDBJ
Genomic DNA
AY903263
EMBL· GenBank· DDBJ
AAX83999.1
EMBL· GenBank· DDBJ
Genomic DNA
AY903264
EMBL· GenBank· DDBJ
AAX84000.1
EMBL· GenBank· DDBJ
Genomic DNA
AY903265
EMBL· GenBank· DDBJ
AAX84001.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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