O76273 · PTP1_ENCHE
- ProteinPolar tube protein 1
- GenePTP1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids453 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Involved in formation of a polar tube through which the infectious agent is passed on to the host cell.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | polar tube | |
Biological Process | sporulation resulting in formation of a cellular spore |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended namePolar tube protein 1
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Fungi > Fungi incertae sedis > Microsporidia > Unikaryonidae > Encephalitozoon
Accessions
- Primary accessionO76273
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-22 | |||||
Sequence: MKGISKILSASIMVMKLGNVYS | ||||||
Chain | PRO_0000022182 | 23-453 | Polar tube protein 1 | |||
Sequence: AVPLCSNTYDPSQQQPSYVLIPSTPEAITNCAYSPKNAYVPSSPTTSSSTPGTNNDNETSPTTEDVGTCKISVVKHCDTPGASSTPCEPEQTIPAQPVTMATVTPAIIASVQTPSVVSVIPVTQKVIQPATMIVPPSSIIPGYYPNGTPAAPGQQGQILSGSVLAPGASSCQLVPGNTPGQMLPGMTPGVSPCLPTQGGDGSNQTIPGIVYPCQPGQGGSGSNQTIPGVISPCQPGQGGSGSNQTIPGIVYPCQPGQGGSGSNQTIPGVISPCQPGQGGSGSNQTIPGIVYPCQPGQNGDGSNQTIPGVISPCQPGQGGNGNGTTGQPGQCVSVPQTPNPIAMPPISGISGNGYPTSTTYTQSLGQLGPCIDVQKPTSSCESQTNEKSTMQYAMEACAAPTPTVVIGNSEYLVGPGMYSSLTSPCNSCCQC | ||||||
Glycosylation | 79 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 225 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 245 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 265 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 285 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 305 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 325 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 344 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Post-translational modification
O-mannosylated. O-mannosylation has functional significance for the ability of microsporidia to invade their host cells.
Keywords
- PTM
PTM databases
Expression
Developmental stage
Found in spores. Expression is high during polar tube formation.
Structure
Family & Domains
Features
Showing features for region, repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 61-87 | Disordered | ||||
Sequence: YVPSSPTTSSSTPGTNNDNETSPTTED | ||||||
Repeat | 214-233 | 1 | ||||
Sequence: PCLPTQGGDGSNQTIPGIVY | ||||||
Region | 214-333 | 6 X 20 AA approximate tandem repeats | ||||
Sequence: PCLPTQGGDGSNQTIPGIVYPCQPGQGGSGSNQTIPGVISPCQPGQGGSGSNQTIPGIVYPCQPGQGGSGSNQTIPGVISPCQPGQGGSGSNQTIPGIVYPCQPGQNGDGSNQTIPGVIS | ||||||
Repeat | 234-253 | 2 | ||||
Sequence: PCQPGQGGSGSNQTIPGVIS | ||||||
Repeat | 254-273 | 3 | ||||
Sequence: PCQPGQGGSGSNQTIPGIVY | ||||||
Repeat | 274-293 | 4 | ||||
Sequence: PCQPGQGGSGSNQTIPGVIS | ||||||
Repeat | 294-313 | 5 | ||||
Sequence: PCQPGQGGSGSNQTIPGIVY | ||||||
Repeat | 314-333 | 6 | ||||
Sequence: PCQPGQNGDGSNQTIPGVIS |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length453
- Mass (Da)45,461
- Last updated1998-11-01 v1
- ChecksumDE519DFC6FF7F963