O61303 · OPSUV_APIME

  • Protein
    Opsin, ultraviolet-sensitive
  • Gene
    UVOP
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

function

Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to 11-cis-retinal.

Absorption

Abs(max) = 353nm

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular FunctionG protein-coupled photoreceptor activity
Molecular Functionphotoreceptor activity
Biological Processcellular response to light stimulus
Biological Processphototransduction
Biological Processvisual perception

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Opsin, ultraviolet-sensitive
  • Alternative names
    • UV-sensitive opsin (AmUVop; BUVOPS)

Gene names

    • Name
      UVOP

Organism names

  • Taxonomic identifier
  • Strain
    • DH4
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Aculeata > Apoidea > Anthophila > Apidae > Apis

Accessions

  • Primary accession
    O61303
  • Secondary accessions
    • Q2YD68

Proteomes

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-52Extracellular
Transmembrane53-73Helical; Name=1
Topological domain74-84Cytoplasmic
Transmembrane85-105Helical; Name=2
Topological domain106-121Extracellular
Transmembrane122-142Helical; Name=3
Topological domain143-161Cytoplasmic
Transmembrane162-182Helical; Name=4
Topological domain183-209Extracellular
Transmembrane210-230Helical; Name=5
Topological domain231-278Cytoplasmic
Transmembrane279-299Helical; Name=6
Topological domain300-302Extracellular
Transmembrane303-323Helical; Name=7
Topological domain324-371Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, glycosylation, disulfide bond, modified residue.

TypeIDPosition(s)Description
ChainPRO_00001976391-371Opsin, ultraviolet-sensitive
Glycosylation3N-linked (GlcNAc...) asparagine
Disulfide bond120↔197
Modified residue318N6-(retinylidene)lysine

Post-translational modification

Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in the dorsal region of the retina.

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Protein family/group databases

Sequence

  • Sequence status
    Complete
  • Length
    371
  • Mass (Da)
    41,458
  • Last updated
    1998-08-01 v1
  • Checksum
    9B2BB1FF92762956
MSNDSIHWEARYLPAGPPRLLGWNVPAEELIHIPEHWLVYPEPNPSLHYLLALLYILFTFLALLGNGLVIWIFCAAKSLRTPSNMFVVNLAICDFFMMIKTPIFIYNSFNTGFALGNLGCQIFAVIGSLTGIGAAITNAAIAYDRYSTIARPLDGKLSRGQVILFIVLIWTYTIPWALMPVMGVWGRFVPEGFLTSCSFDYLTDTNEIRIFVATIFTFSYCIPMILIIYYYSQIVSHVVNHEKALREQAKKMNVDSLRSNANTSSQSAEIRIAKAAITICFLYVLSWTPYGVMSMIGAFGNKALLTPGVTMIPACTCKAVACLDPYVYAISHPKYRLELQKRLPWLELQEKPISDSTSTTTETVNTPPASS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF004169
EMBL· GenBank· DDBJ
AAC13418.1
EMBL· GenBank· DDBJ
mRNA
AADG06009813
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BK005513
EMBL· GenBank· DDBJ
DAA05738.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp