O32953 · COBT_MYCLE
- ProteinNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
- GenecobT
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids351 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
Catalytic activity
- 5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide = alpha-ribazole 5'-phosphate + nicotinate + H+
Pathway
Nucleoside biosynthesis; alpha-ribazole biosynthesis; alpha-ribazole from 5,6-dimethylbenzimidazole: step 1/2.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 313 | Proton acceptor | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity | |
Biological Process | cobalamin biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
- EC number
- Short namesNN:DBI PRT
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium
Accessions
- Primary accessionO32953
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000167055 | 1-351 | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | |||
Sequence: MEFAPVSPPDGHAAAAARARQDTLTKPRGALGRLEDLSIWVASCQGQCPPRQFQRARIVVFAGDHGVARSGVSAYPPQLTAQMVANIDRGGAAINALASIADATIRIADLAVDADPLSQQIGIHKVRRGSGDIAIQDALTEDETARAIIAGQRIADEEVDRGADLLIAGDIGIGNTTAAAVLVAALTNAEPVAVVGFGTGIDDASWARKTAAVRDALCRIRLVLPDPVGLLRCCGGADLAAMAGFCAQAAVRRTPLLLDGMVVTAAALVAERLAPGSWQWWQAGHQSTEPGHALALAALDLDPILDLRMRLGEGTGATAALLVLRAAVAALTSMTTFAEAGVAGTSTSPPS |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length351
- Mass (Da)36,017
- Last updated1998-01-01 v1
- Checksum919231520D5FE2A0
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
Z98741 EMBL· GenBank· DDBJ | CAB11373.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AL583920 EMBL· GenBank· DDBJ | CAC31249.1 EMBL· GenBank· DDBJ | Genomic DNA |