O32177 · FADA_BACSU

Function

function

Involved in the degradation of long-chain fatty acids.

Catalytic activity

Pathway

Lipid metabolism; fatty acid beta-oxidation.

Features

Showing features for active site.

139150100150200250300350
TypeIDPosition(s)Description
Active site90Acyl-thioester intermediate
Active site347Proton acceptor
Active site377Proton acceptor

GO annotations

AspectTerm
Molecular Functionacetyl-CoA C-acyltransferase activity
Biological Processfatty acid beta-oxidation
Biological Processphenylacetate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-ketoacyl-CoA thiolase
  • EC number
  • Alternative names
    • Acetyl-CoA acyltransferase
    • Beta-ketothiolase

Gene names

    • Name
      fadA
    • Synonyms
      yusK
    • Ordered locus names
      BSU32830

Organism names

Accessions

  • Primary accession
    O32177

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003606691-3913-ketoacyl-CoA thiolase

Proteomic databases

Expression

Induction

Repressed by FadR in the absence of LCFAs (fatty acids of 14-20 carbon atoms). When LCFAs are present in the medium, they are converted to long-chain acyl-CoAs, which antagonize FadR as to its binding to fadR boxes on target DNA and thus derepress transcription.

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    391
  • Mass (Da)
    41,123
  • Last updated
    1998-01-01 v1
  • Checksum
    B326A3D6A64E5799
MKEAVIVSGARTPVGKAKKGSLATVRPDDLGAICVKETLKRAGGYEGNIDDLIIGCATPEAEQGLNMARNIGALAGLPYTVPAITVNRYCSSGLQSIAYAAEKIMLGAYDTAIAGGAESMSQVPMMGHVTRPNLALAEKAPEYYMSMGHTAEQVAKKYGVSREDQDAFAVRSHQNAAKALAEGKFKDEIVPVEVTVTEIGEDHKPMEKQFVFSQDEGVRPQTTADILSTLRPAFSVDGTVTAGNSSQTSDGAAAVMLMDREKADALGLAPLVKFRSFAVGGVPPEVMGIGPVEAIPRALKLAGLQLQDIGLFELNEAFASQAIQVIRELGIDEEKVNVNGGAIALGHPLGCTGTKLTLSLIHEMKRRNEQFGVVTMCIGGGMGAAGVFELC

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL009126
EMBL· GenBank· DDBJ
CAB15272.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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