M0K7V5 · M0K7V5_9EURY

Function

function

Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.

Catalytic activity

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis.

Features

Showing features for binding site.

124920406080100120140160180200220240
TypeIDPosition(s)Description
Binding site20ATP (UniProtKB | ChEBI)
Binding site42ATP (UniProtKB | ChEBI)
Binding site183-185ATP (UniProtKB | ChEBI)
Binding site189-190ATP (UniProtKB | ChEBI)
Binding site201-202ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionacid-amino acid ligase activity
Molecular FunctionATP binding
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-phosphopantoate--beta-alanine ligase
  • EC number
  • Alternative names
    • Phosphopantothenate synthetase
      (PPS
      )

Gene names

    • ORF names
      C436_02457
      , KDQ40_01820

Organism names

  • Taxonomic identifier
  • Strain
    • ATCC 33800
  • Taxonomic lineage
    Archaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloarculaceae > Haloarcula

Accessions

  • Primary accession
    M0K7V5

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the archaeal phosphopantothenate synthetase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    249
  • Mass (Da)
    26,723
  • Last updated
    2013-04-03 v1
  • Checksum
    46381A69F12ED408
MSEDVDLPESHPRYESLLTRHRIEAGVDRGITSRQGLIAQGRGEAFDYLLGERTIDSADDAERAAAAHLLSADHAVVSVNGNAAALVPGELVELAEVTGADLEVNLFNRTEERIEAIAEYLREHGATDVRGLTADGRIPGLDHERAKVDADGIGAADVVLVPLEDGDRAEALGEMGKTELVIDLNPRSRSAEVATVPIIDNIIRAIPNITEHARDLRGDPDAQQDAIDTFDADSALTAAERTIREGDLE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AOLR01000003
EMBL· GenBank· DDBJ
EMA15910.1
EMBL· GenBank· DDBJ
Genomic DNA
CP073366
EMBL· GenBank· DDBJ
QUJ72517.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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