K8A4L6 · K8A4L6_9ENTR
- ProteinAconitate hydratase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids891 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
Catalytic activity
- citrate = D-threo-isocitrate
Cofactor
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | aconitate hydratase activity | |
Molecular Function | iron-responsive element binding | |
Molecular Function | metal ion binding | |
Biological Process | citrate metabolic process | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAconitate hydratase
- EC number
- Short namesAconitase
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Cronobacter
Accessions
- Primary accessionK8A4L6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 69-562 | Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha | ||||
Sequence: WLEHAHTDREIAYRPARVLMQDFTGVPAVVDLAAMREAVQRLGGDVSKVNPLSPVDLVIDHSVTVDHFGDDNAFEENVRLEMERNHERYAFLRWGQQAFSRFSVVPPGTGICHQVNLEYLGKAVWSEMQDGAMVAYPDTLVGTDSHTTMINGLGVLGWGVGGIEAEAAMLGQPVSMLIPDVVGFRLTGKLSEGITATDLVLTVTQMLRKHGVVGKFVEFFGDGLDSLPLADRATIANMAPEYGATCGFFPIDDVTLGYLRLSGRSEEQVALVETYAKAQGMWRNPGDEPVFTSTLELDMGTVEASIAGPKRPQDRVGLGDVPKAFAASTELEVNSPKNDLHSVGYVLSGHQYELPDGAVVIAAITSCTNTSNPSVLMAAGLLAKKAVKLGLKRQPWVKASLAPGSKVVSDYLAHAKLTPWLDELGFNLVGYGCTTCIGNSGPLPEPIEQAIKKGDLTVGAVLSGNRNFEGRIHPLVKTNWLASPPLVVAYALAG | ||||||
Domain | 691-818 | Aconitase A/isopropylmalate dehydratase small subunit swivel | ||||
Sequence: RYLQSHGVERGDFNSYGSRRGNHEVMMRGTFANIRIRNEMVPGVEGGMTRLIPGNEVMSIYDAAMRYQAQGTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESFERIHRSNLIGMGILPLEFPQ |
Sequence similarities
Belongs to the aconitase/IPM isomerase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length891
- Mass (Da)97,076
- Last updated2013-02-06 v1
- Checksum81FDEB4218088AB3
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CAKW01000144 EMBL· GenBank· DDBJ | CCJ74680.1 EMBL· GenBank· DDBJ | Genomic DNA |