K2HL09 · K2HL09_9RHOB

Function

function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FMN (UniProtKB | Rhea| CHEBI:58210 )

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site30-32FMN (UniProtKB | ChEBI)
Binding site83FMN (UniProtKB | ChEBI)
Active site113Proton donor
Binding site152FMN (UniProtKB | ChEBI)
Binding site182FMN (UniProtKB | ChEBI)
Binding site237-238FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctionRNA binding
Molecular FunctiontRNA dihydrouridine synthase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-dihydrouridine synthase
  • EC number

Gene names

    • ORF names
      OCGS_2316

Organism names

Accessions

  • Primary accession
    K2HL09

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain27-301DUS-like FMN-binding

Sequence similarities

Belongs to the dus family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    334
  • Mass (Da)
    34,286
  • Last updated
    2012-11-28 v1
  • Checksum
    0EB190BB7BA1C172
MKPSRPVPDADDRAAALRALGIDMPVLLAPMAGITDLPFRNIVAGFGAGLVTSEMVASDALNGGSAATIAKVSGAGRQDTSVQIAGRQPAEMTEAARRVADAGARIVDINMGCPAKRVTGGLSGSALMRDPDHALRLIDAVARAVAVPVTLKMRLGWDGDCLTAPQIARRAEAAGIRMVTVHGRTRCQFYKGRADWTAIRAVADAVTIPVVANGDICDAADARAALAASGAQAVMVGRGAQGRPWALAEIGAALAGADTPPVPADLTALALAHLDAARSFYGADLGARTMRKHLGWYMDHAGTPPDLRRAVLTAPPARLPALLDAALAPGRLAA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AMGO01000052
EMBL· GenBank· DDBJ
EKE43584.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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