J8Q1C8 · J8Q1C8_SACAR
- ProteinThi6p
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids540 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H+ = CO2 + diphosphate + thiamine phosphate
Cofactor
Pathway
Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.
Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | hydroxyethylthiazole kinase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | thiamine-phosphate diphosphorylase activity | |
Biological Process | thiamine biosynthetic process | |
Biological Process | thiamine diphosphate biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces
Accessions
- Primary accessionJ8Q1C8
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 12-212 | Thiamine phosphate synthase/TenI | ||||
Sequence: LYLVTDSTMLPPGTTLCSQVEAGLKNGVTLVQIREKDTETKNFIEEALEVQKICKKYNVPLIINDRIDVAMAIDADGVHVGQEDMPIPMVRKLLGSSKILGWSVGKRSEVETLAKWGPDMVDYVGVGTLFPTLTKKNPKKTPMGTQGAISVLNALEEFKATWCRTVGIGGIHPDNIQRVICQCVSSNGKRSLDGISLVSDI |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length540
- Mass (Da)58,014
- Last updated2012-10-31 v1
- Checksum9356D5D54193C060
Keywords
- Technical term