J7Q4S5 · J7Q4S5_METSZ

Function

function

Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 1/3.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site61-64carbamoyl phosphate (UniProtKB | ChEBI)
Binding site88carbamoyl phosphate (UniProtKB | ChEBI)
Binding site112carbamoyl phosphate (UniProtKB | ChEBI)
Binding site139-142carbamoyl phosphate (UniProtKB | ChEBI)
Binding site170L-ornithine (UniProtKB | ChEBI)
Binding site230L-ornithine (UniProtKB | ChEBI)
Binding site234-235L-ornithine (UniProtKB | ChEBI)
Binding site269-270carbamoyl phosphate (UniProtKB | ChEBI)
Binding site297carbamoyl phosphate (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functionamino acid binding
Molecular Functionornithine carbamoyltransferase activity
Biological Processarginine biosynthetic process via ornithine
Biological Processcitrulline biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ornithine carbamoyltransferase
  • EC number
  • Short names
    OTCase

Gene names

    • Name
      argF
    • Ordered locus names
      BN69_2413

Organism names

  • Taxonomic identifier
  • Strain
    • SC2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Methylocystaceae > Methylocystis

Accessions

  • Primary accession
    J7Q4S5

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-152Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Domain159-308Aspartate/ornithine carbamoyltransferase Asp/Orn-binding

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    314
  • Mass (Da)
    34,301
  • Last updated
    2012-10-31 v1
  • Checksum
    A68CCE104E6C7A27
MTAHSLTRPRSFLDLSDHSGEELRRILNLATSLKARRVKGVAPTERPLAGKYLGMVFDKPSTRTRVSFDIAMRELGGETIMLTGAEMQLGRGETIADTARVLSRFLDAIMVRILSHPDLMELARFGNLPVINGLTKQSHPCQVMADVLTFEEHLGPIEGRIVAWSGDANNVLTSWVHAAGRLGFTINVATPANFAPSEELMGWAKTNGAKINLTRDAYEAVAGADAVITDCWVSMGDADEDQRRAALAPYQVDSKLMRAAAKHAIFMHCLPAHRGEEVTAEVIDGPQSVVFDEAENRLHAQKGVLCWCLAPGQF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HE956757
EMBL· GenBank· DDBJ
CCJ07864.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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