J7MPV6 · J7MPV6_9CHLO

Function

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

One-carbon metabolism; tetrahydrofolate interconversion.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular FunctionFAD binding
Molecular Functionmethylenetetrahydrofolate reductase (NAD(P)H) activity
Biological Processmethionine biosynthetic process
Biological Processtetrahydrofolate interconversion

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • Methylenetetrahydrofolate reductase

Gene names

    • Name
      mthfr

Organism names

  • Taxonomic identifier
  • Strain
    • Pringsheim 198.80
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Chlorophyta > core chlorophytes > Chlorophyceae > CS clade > Chlamydomonadales > Chlamydomonadaceae > Polytomella

Accessions

  • Primary accession
    J7MPV6

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain310-366MTHFR SAM-binding regulatory
Domain390-623MTHFR SAM-binding regulatory

Sequence similarities

Belongs to the methylenetetrahydrofolate reductase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    629
  • Mass (Da)
    70,051
  • Last updated
    2012-10-31 v1
  • Checksum
    C851F9A7FC524649
MKIIDKINLKIEERRPFFSFEFFPPRTEEGVENLFERQERLVSYGPVFCDITWGAGGSTADVTQDIAVKMQNLVGVETMMHLTCTNMPKERLEIALKEVQKAGVKNILALRGDAPKGQDKFEAIEGGFSCALDLVKYIKKEFGSYFGIGVAGYPEAHPDSIVDDPEQMKKNYFENIEYLKKKVDAGADFIITQLFYDANIFIKFMNDCRAAGITCPILPGIMPIASYAGFKRMTSFCKTHVPQHILDAVEAIKDDEEAIKNFGISYGVEMCRKVLAAGAPGVHLYTLNLERSAVGIVEKLGIMPEQLGSRFPLPWRPASIGTDRTNEGVRPIFWANRPKSYVLRTSHWTEFPSKSWTSKLLASAAFDSSVDQKPLSDAVNVATVTEASLASHVIGDVNKYQMTRHICSTLRQERSRASWGIEVSNVEAVKDVFAKFYLGELRGLPWFEHDVPGAAAASIELREQLAVLCRKGILVMNCQPSARETPATDPVVGWGPTKGYVYQKAYLEFFVAPEAFRSLLPVLQGKENVTYMASDVRGEIFHSNAAPGDVNAVTWGVFPGHELVQPFVATLPAFLSWRDEAFALWDEDWAALYPEGSVSRTVLKAIHDTYVLVSITENDFVNGDLLSKF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FR690275
EMBL· GenBank· DDBJ
CBX19675.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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