J6ELC4 · J6ELC4_TRIAS

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Pathway

Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site125substrate
Binding site143ATP (UniProtKB | ChEBI)
Binding site143Mg2+ (UniProtKB | ChEBI)
Binding site145Mg2+ (UniProtKB | ChEBI)
Binding site147-150substrate
Binding site221-223substrate
Binding site227substrate
Binding site288-291substrate
Binding site327ATP (UniProtKB | ChEBI)
Binding site398-407ATP (UniProtKB | ChEBI)
Binding site402Mg2+ (UniProtKB | ChEBI)
Binding site409ATP (UniProtKB | ChEBI)
Binding site431-434ATP (UniProtKB | ChEBI)
Binding site460ATP (UniProtKB | ChEBI)
Binding site486substrate
Binding site488ATP (UniProtKB | ChEBI)
Binding site494ATP (UniProtKB | ChEBI)
Binding site497-498substrate

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionglutathione binding
Molecular Functionglutathione synthase activity
Molecular Functionmagnesium ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione synthetase
  • EC number
  • Short names
    GSH-S

Gene names

    • ORF names
      A1Q1_06556

Organism names

Accessions

  • Primary accession
    J6ELC4

Proteomes

Organism-specific databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain212-324Glutathione synthase substrate-binding

Sequence similarities

Belongs to the eukaryotic GSH synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    510
  • Mass (Da)
    55,838
  • Last updated
    2012-10-31 v1
  • Checksum
    316C6A31AC951A8C
MPALPTWPPELSDVQRETLLRESSVWALAHGFTLLPPSPSDPPTSTIAAPLSLLPSPFPRAEYEKARRIQTAYNALYARVALDTAFLDKVMQDVAPVDAFQAELWSRWKEIRDDLAQPLQLGLFRSDYLLHTEGDRAEIKQVEFNTIAASFGALSQKAGEMHRFLAQKTEGFFQPPRSLLEDKSAYPLNRSAEGLAGGLLGGWAAYGRDKAAVLFVVQPGERNVFDQRGLEYILSSKGVRVIRMTFAELGANARVGPEGRLFVRDLEGAQGVQGAQGKQFEIAVVYYRAAYTPDDYKSAKDWDTRVLLEKSTAIKCPSMALQLAGAKKVQQELAQPGVLEDFLLGKNRPAVGLQQPLTQQDVDALRDTWTGLWPMDDSELGKEAARLAQEEPERFVLKPQREGGGNNIYRKDIPGHLAKLGPGEKNGYILMELIEPPQGVHNWLVRGGEGIARYADIVSELGVYGVALFGGDDSAAVNAEVGTLLRTKGRESDEGGVAIGISSIDSPILV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ALBS01000337
EMBL· GenBank· DDBJ
EJT45064.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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