I3Y6B5 · I3Y6B5_THIV6

Function

function

Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functionlipid-linked peptidoglycan transporter activity
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable lipid II flippase MurJ

Gene names

    • Name
      murJ
    • Ordered locus names
      Thivi_0472

Organism names

Accessions

  • Primary accession
    I3Y6B5

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane92-118Helical
Transmembrane130-152Helical
Transmembrane158-180Helical
Transmembrane187-210Helical
Transmembrane275-293Helical
Transmembrane314-335Helical
Transmembrane355-376Helical
Transmembrane383-404Helical
Transmembrane410-431Helical
Transmembrane443-462Helical
Transmembrane482-502Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the MurJ/MviN family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    511
  • Mass (Da)
    54,748
  • Last updated
    2012-09-05 v1
  • Checksum
    0670A867421B80CF
MASLAASLAKVGGNTLLSRILGFARDLVVAHAFGADAGTDAFFVAFKIPNFMRRLFAEGAFSMAFVPVLNAYRETHGFPALKHFVDDIAGTFGAVLLLITALGVLGAPVLILIFAPGFAHDVAQWELATAMLRLTFPYVLFISLTALAGGILNTYERFGIPAFTPVLLNLSLIGCTIVLAPRMEQPIMALAWGVLFAGMIQLAFQLPFLAQLDLLPRPRLTRKDPGIGQVIRRMGPALFGVSVAQISLLLDTLLASFLTTGSISWLYYSDRLMEFPLGILAATLGTVILPRLSRRHAANDPESFSETLNWALRWILLLGVPAAVGLLVLAGPLMATLFHSGEFNADDVAMASHSLMAYSLGLIGFMGIKVLAPGYYARQEMKIPARIAAIALLVGLGCNLILMIPLGHAGLALGTTIAAMLNAGLLLRGLLKDGILRPQAGWIVLLARGLTASLIMGCVIHLGADDTARWIAMDSGERIRHLLTWIALGGFVYLAALLALGIRPRHLRART

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003154
EMBL· GenBank· DDBJ
AFL72533.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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