I3REA5 · I3REA5_9EURY
- ProteinProline permease
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids492 (go to sequence)
- Protein existenceInferred from homology
- Annotation score1/5
Function
Catalytic activity
- L-proline(in) + Na+(in) = L-proline(out) + Na+(out)L-proline (in)CHEBI:60039
+ Na+ (in)CHEBI:29101= L-proline (out)CHEBI:60039+ Na+ (out)CHEBI:29101
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | proline:sodium symporter activity | |
Molecular Function | sodium ion binding | |
Biological Process | proline transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Thermococci > Thermococcales > Thermococcaceae > Pyrococcus
Accessions
- Primary accessionI3REA5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 12-32 | Helical | ||||
Sequence: VAFTAFLFTLLLPILVGFLVM | ||||||
Transmembrane | 53-75 | Helical | ||||
Sequence: VALSAVSSGRSSWLVLGLSGMAY | ||||||
Transmembrane | 81-101 | Helical | ||||
Sequence: AVWAAVGYITVEMLQFVYMGM | ||||||
Transmembrane | 129-148 | Helical | ||||
Sequence: IVRLVVSIIIVIFLTSYVGA | ||||||
Transmembrane | 160-182 | Helical | ||||
Sequence: ALGISLFTGLIIAVLMIVVYMVL | ||||||
Transmembrane | 194-215 | Helical | ||||
Sequence: IRAVIMIIGLTVLPVVAVAKVG | ||||||
Transmembrane | 235-254 | Helical | ||||
Sequence: WAFGAGVVIGFLGIGLGSPG | ||||||
Transmembrane | 275-300 | Helical | ||||
Sequence: TVIGTFWNVVLAWGAVFVGLAGRALV | ||||||
Transmembrane | 320-340 | Helical | ||||
Sequence: AQYFGPLLYGILMGGIFAAIL | ||||||
Transmembrane | 377-395 | Helical | ||||
Sequence: ISRLTVLVIGFLAAILAYY | ||||||
Transmembrane | 401-424 | Helical | ||||
Sequence: FWFVLFAWGGLGASIGPTLLLSLY | ||||||
Transmembrane | 431-450 | Helical | ||||
Sequence: WGVVAGMIVGTITTIVWKLY | ||||||
Transmembrane | 456-478 | Helical | ||||
Sequence: GLYELVPAFIFALLATIIVSLLT |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length492
- Mass (Da)53,694
- Last updated2012-09-05 v1
- ChecksumD24374BB29A3661E
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP003534 EMBL· GenBank· DDBJ | AFK22565.1 EMBL· GenBank· DDBJ | Genomic DNA |