I3PFJ3 · DOD1U_BETVU
- Protein4,5-DOPA dioxygenase extradiol 1
- GeneDODA1
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids275 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
function
Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid.
Catalytic activity
- L-dopa + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H+
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Pigment biosynthesis; betalain biosynthesis.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ferrous iron binding | |
Molecular Function | stizolobate synthase activity | |
Molecular Function | zinc ion binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name4,5-DOPA dioxygenase extradiol 1
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > Caryophyllales > Chenopodiaceae > Betoideae > Beta
Accessions
- Primary accessionI3PFJ3
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000431981 | 1-275 | 4,5-DOPA dioxygenase extradiol 1 | |||
Sequence: MKMMNGEDATDQMIKESFFITHGNPILTVEDTHPLRPFFETWREKIFSKKPKAILIISGHWETVKPTVNAVHINDTIHDFDDYPAAMYLFKYPAPGAPELARKVEEILKKSGFETAETDEKRGLDHGAWVPLMLMYPEADIPVCQLSVQPHLDGTYHYNLGRALAPLKNDGVLIIGSGSATHPLDETPHYFDGVAPWAAAFDSWLRKALINGRFEEVNIYETKAPNWKLAHPFPEHFYPLHVVLGAAGEKWKAELIHSSWDHGTLCHGSYKFTSA |
Expression
Induction
Regulated by MYB1.
Structure
Sequence
- Sequence statusComplete
- Length275
- Mass (Da)31,090
- Last updated2012-09-05 v1
- ChecksumB3BCF806733ABB8F