I2H7L8 · I2H7L8_HENB6

Function

function

Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

Pathway

Protein modification; protein lipoylation via endogenous pathway; protein N6-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.

Features

Showing features for site, active site.

TypeIDPosition(s)Description
Site237Lowers pKa of active site Cys
Active site271Acyl-thioester intermediate

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionlipoyl(octanoyl) transferase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Octanoyltransferase
  • EC number

Gene names

    • Name
      TBLA0H00810
    • ORF names
      TBLA_0H00810

Organism names

Accessions

  • Primary accession
    I2H7L8

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain107-312BPL/LPL catalytic

Sequence similarities

Belongs to the LipB family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    336
  • Mass (Da)
    38,311
  • Last updated
    2012-07-11 v1
  • Checksum
    5EA437735BEC2F61
MFSSRICVRPFVEPCLRLNQLQKYLSSVALTRPKNESAKLLRHLQFTERIPFQDGLEIQEKFVRAQLDMKKLERKIQDKMQEIGDEHGPNAILNENEKKIIDYILMMKPNPIVLTFEFEPTFTGGKRIKKTITKEQIERFETFTTSGNHIKPKFVLVERGGQITFHGPGQMVAYVILDLQSFKNLRARDLVCILEKSMVRGLSMLKNNQDDSAALSLLTESRTGSETGIWIKNTNKKIGSLGINVRRSVTSHGVCINVEPDLAYLNNFRKCSGLPNCEATSINDQLPGSNINVQDMAIAFTKELAKHLGIERLERIQMTLEDMNLDNEQLENNDSK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HE806323
EMBL· GenBank· DDBJ
CCH62370.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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