I2DPQ4 · I2DPQ4_9BURK

  • Protein
    nicotinate-nucleotide diphosphorylase (carboxylating)
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Involved in the catabolism of quinolinic acid (QA).

Pathway

Cofactor biosynthesis; NAD+ biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.

Features

Showing features for binding site.

129320406080100120140160180200220240260280
TypeIDPosition(s)Description
Binding site114substrate
Binding site147-149substrate
Binding site171substrate
Binding site181substrate
Binding site210substrate
Binding site231substrate
Binding site254-256substrate
Binding site275-277substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functionnicotinate-nucleotide diphosphorylase (carboxylating) activity
Biological ProcessNAD biosynthetic process
Biological Processquinolinate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    nicotinate-nucleotide diphosphorylase (carboxylating)
  • EC number
  • Alternative names
    • Quinolinate phosphoribosyltransferase [decarboxylating]

Gene names

    • ORF names
      MYA_2270

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KJ006
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia

Accessions

  • Primary accession
    I2DPQ4

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain42-124Quinolinate phosphoribosyl transferase N-terminal
Domain126-290Quinolinate phosphoribosyl transferase C-terminal

Sequence similarities

Belongs to the NadC/ModD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    293
  • Mass (Da)
    31,586
  • Last updated
    2012-07-11 v1
  • Checksum
    384AA16695A598BB
MSDAVSPLFDSVRVQYGAAFDEAIARNVADAIAEDVGACDQTGRLVPADERRRARIIVREEAVLCGVPWFEAVIARIDPSIVVQWRYREGDRMTADSTVCELDGPARALLTAERNGLNFLQLLSGVATATRRYVDRVEGTRAKILDTRKTLPGLRLAQKYAVRVGGGENQRLALYDGILIKENHIAAAGGVGEALDAAFALNAGVPVQIEVETLAQLDTALAHGAQSVLLDNFTLDMMREAVRVAAGKAVLEVSGGVNFDTVRTFAETGVDRISIGALTKDVRATDYSMRIVD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003514
EMBL· GenBank· DDBJ
AFJ86630.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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