I0Q2F1 · I0Q2F1_STROR

Function

function

Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Preferential cleavage: (Ac)2-L-Lys-D-Ala-|-D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine.
    EC:3.4.16.4 (UniProtKB | ENZYME | Rhea)

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for active site, binding site.

141350100150200250300350400
TypeIDPosition(s)Description
Active site56Acyl-ester intermediate
Active site59Proton acceptor
Active site119
Binding site239substrate

GO annotations

AspectTerm
Molecular Functionserine-type D-Ala-D-Ala carboxypeptidase activity
Biological Processpeptidoglycan biosynthetic process
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    serine-type D-Ala-D-Ala carboxypeptidase
  • EC number

Gene names

    • ORF names
      HMPREF1115_0638

Organism names

  • Taxonomic identifier
  • Strain
    • SK610
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus

Accessions

  • Primary accession
    I0Q2F1

Proteomes

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-22
ChainPRO_500363191423-413serine-type D-Ala-D-Ala carboxypeptidase

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain293-394Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal

Sequence similarities

Belongs to the peptidase S11 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    413
  • Mass (Da)
    45,009
  • Last updated
    2012-06-13 v1
  • Checksum
    A0363A12059303AB
MKKIILSFITLLVFGTASTVSAQEFDVAAKHAIAVEATTGKILYEKDANQPVEIASITKLVTVYLVYEALEQGTIGLSTPVDISDYPYKLTTNSEASNVPMEARNYTVEQLLEATMVSSANSAAIALAEKIAGSEKDFVDKMRAKLLEWGIQDATIVNTTGLNNETLGDNIYPGSKKDDENKLSAYDVAIVARNLIRDYPQVLEITKKPTSTFAGLEIHSTNYMLEGMPAYRGGIDGLKTGTTDKAGASFVGTTVEKGMRIITVVLNADQQDTNPYARFTATSALLDYISANFALKTVVQKGEAYNDSKVTVLDGKEDNVTAVAKSDISIVQRIGSGTTPALQFTPKSTSEMAPLEEGKVVGTLTYDDQDLVGQGYLTSDKPSFEMVSEKKVEKAFFLKVWWNQFIRFINEKL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJKQ01000019
EMBL· GenBank· DDBJ
EIC75453.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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