H1KWJ9 · H1KWJ9_9EURY
- ProteinCDP-archaeol synthase
- GenecarS
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids179 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Catalytic activity
- 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + CTP + H+ = CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol + diphosphate
Cofactor
Pathway
Membrane lipid metabolism; glycerophospholipid metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity | |
Biological Process | glycerophospholipid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCDP-archaeol synthase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Methanomada group > Methanococci > Methanococcales > Methanocaldococcaceae > Methanotorris
Accessions
- Primary accessionH1KWJ9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 6-29 | Helical | ||||
Sequence: LVFSSFWYILPAYIANATACIFGG | ||||||
Transmembrane | 50-72 | Helical | ||||
Sequence: VTFRGTFSGILCGTIAAILQGVI | ||||||
Transmembrane | 84-105 | Helical | ||||
Sequence: FYSNIFECAFLGFLLSSGALFG | ||||||
Transmembrane | 150-170 | Helical | ||||
Sequence: MIITICVITPIIHLTSNIIAY |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length179
- Mass (Da)19,704
- Last updated2012-03-21 v1
- Checksum3E7D148731554E47
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AGJL01000002 EMBL· GenBank· DDBJ | EHP89576.1 EMBL· GenBank· DDBJ | Genomic DNA |