H1HGD2 · H1HGD2_9FUSO
- ProteinUrocanate reductase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids573 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- A + dihydrourocanate = AH2 + urocanate
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 FAD per subunit.
Note: Binds 1 or 2 FMN covalently per subunit.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | FMN binding | |
Molecular Function | oxidoreductase activity | |
Biological Process | steroid metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUrocanate reductase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Fusobacteriota > Fusobacteriia > Fusobacteriales > Fusobacteriaceae > Fusobacterium
Accessions
- Primary accessionH1HGD2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-26 | |||||
Sequence: MKKNFFGKLFGLTLLMFTLLFTGASA | ||||||
Chain | PRO_5022260833 | 27-573 | Urocanate reductase | |||
Sequence: ETYEGTGLGYDKDGIVLDVEITNNKIVDVKVKRAKESEFATSAIQKIAKKVIATQSLDVDGVSGASLTSEGTKEAIEEAVKKSGVTLTAVTLQNTKAVELPKEADVVVIGAGGAGLTSAIAAHEKGAKVILIEKTELLGGNTNYATAGLNAAGTKIQEKLGIKDSPELFYEDTMKGGKNKNNKELVRVLVNNSSAIVDWLTERGADLSELTSTGGQSVKRTHRPTGGSAVGPNIVAALSKTAESEKIDIRKGTKAIALVKAKNRIVGVKVREIDGKEYTIKAKAVIVATGGFGANAKMVEKYNPKLKGFGSTNNPAIVGDGIIMVEKVGGALVDMSEIQTHPTVVHNKTNMITEAVRGEGAILVNRDGKRFIDELETRDVVSKAILNQKGKLAFLIFDEGIRTKLKAADGYVKKGFAVEGTLEEIAAKIGTDAKTLEATLNKYNEAVRNKVDSEFNKKTLPKELTGTKYYAIEVSPAVHHTMGGVRINTNAEVLGKNGRPIKGLYAAGEVTGGIHGANRIGGNAVADITIFGKIAGENAAIYSKSVK |
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 35-109 | FMN-binding | ||||
Sequence: GYDKDGIVLDVEITNNKIVDVKVKRAKESEFATSAIQKIAKKVIATQSLDVDGVSGASLTSEGTKEAIEEAVKKS | ||||||
Region | 237-256 | Disordered | ||||
Sequence: TSTGGQSVKRTHRPTGGSAV |
Sequence similarities
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length573
- Mass (Da)60,618
- Last updated2012-03-21 v1
- Checksum7C49700E9996D2D4
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AGEH01000021 EMBL· GenBank· DDBJ | EHO76913.1 EMBL· GenBank· DDBJ | Genomic DNA |